Development of a Gustatory Function Test for Clinical Application in Korean Subjects

被引:21
作者
Hwang, Chi Sang [1 ]
Kim, Jin Won [1 ]
Al Sharhan, Salma Saud [2 ,3 ]
Kim, Jin Woong [2 ,3 ]
Cho, Hyung-Ju [1 ,4 ,5 ]
Yoon, Joo-Heon [1 ,4 ,5 ]
Kim, Chang-Hoon [1 ,4 ,5 ,6 ]
机构
[1] Yonsei Univ, Coll Med, Dept Otorhinolaryngol, 50-1 Yonsei Ro, Seoul 03722, South Korea
[2] Imam Abdulrahman Bin Faisal Univ, Dept Otorhinolaryngol, Al Khobar, Saudi Arabia
[3] King Fahad Cent Hosp, Al Khobar, Saudi Arabia
[4] Yonsei Univ, Coll Med, Airway Mucus Inst, Seoul, South Korea
[5] Korea Mouse Sensory Phenotyping Ctr, Seoul, South Korea
[6] Yonsei Univ, Coll Med, Med Res Ctr, Seoul, South Korea
基金
新加坡国家研究基金会;
关键词
Taste; gustation; validated clinical value; umami; SMELL IDENTIFICATION TEST; ODOR IDENTIFICATION; TASTE; DISCRIMINATION; THRESHOLDS;
D O I
10.3349/ymj.2018.59.2.325
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: To obtain validated clinical values suitable for developing a gustatory function test, including umami taste, in a Korean population. Materials and Methods: The investigation involved 297 participants with self-reported normal sense of taste and smell. Liquid solutions were used for the assessment of gustatory function. The test consisted of 30 taste solutions [six concentrations of five tastants (sweet, bitter, salty, sour, and umami)]. For evaluation of overall gustatory function, the number of detected or correctly recognized taste thresholds was combined to form a "taste score." Results: Mean values of each detection and recognition threshold for the five tastes in men were consistently lower than those of women. The 10th percentile of taste score for recognition was used as the cut-off value for distinguishing normogeusia from hypogeusia. In subgroup analysis, total taste score from recognition thresholds revealed a significant negative correlation with age, indicating lower scores for increasing age. Taste score for non-smokers was significantly higher than that of smokers, in terms of detection and recognition of taste sensitivities. Conclusion: This gustatory function test was easy to perform, affordable, and time-saving, with the capacity to self-produce and obtain reliable data. Gustatory function was more sensitive in young people, women, and non-smokers.
引用
收藏
页码:325 / 330
页数:6
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