Autologous Stem Cell Transplantation for T-Cell Lymphomas

被引：17

作者：

Giulia, Perrone ^{[1
]}

Corradini, Paolo ^{[1
,2
]}

机构：

[1] Fdn IRCCS, Ist Nazl Tumori, Div Hematol, I-20133 Milan, Italy

[2] Univ Milan, Dept Hematol, Milan, Italy

来源：

SEMINARS IN HEMATOLOGY | 2014年 / 51卷 / 01期

关键词：

HIGH-DOSE CHEMOTHERAPY; NON-HODGKINS-LYMPHOMA; MARROW TRANSPLANTATION; COMPLETE REMISSION; CLINICAL-OUTCOMES; PROGNOSTIC INDEX; UP-FRONT; THERAPY; EXPERIENCE; REGIMEN;

D O I：

10.1053/j.seminhematol.2013.11.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Peripheral T-cell lymphomas (PTCLs) are a rare and heterogeneous group of T-cell malignancies characterized by a very poor outcome. The optimal treatment for PTCLs remains controversial. The role of stem cell transplantation in PTCLs has been investigated; however, no randomized control studies specifically dedicated to PTCLs are currently available. Several retrospective and-prospective studies have suggested that high-dose chemotherapy (HDT) followed by autologous stem cell transplantation (ASCT) may improve the survival in patients with chemosensitive T-cell lymphoma, either upfront or as salvage treatment. This review provides a summary of the current literature with the intent to explore the role of ASCT in various clinical scenarios. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：59 / 66

页数：8

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