Fabrication of CaSiO3 bioceramics with open and unidirectional macro-channels using an ice/fiber-templated method

Porous CaSiO3 bioceramics with open and unidirectional macro-channels of pore size more than 200 mu m are of particular interest for biomedical applications. An ice/fiber-templated method was employed for the fabrication of CaSiO3 bioceramics with interconnected lamellar pores and macro-channels of pore size more than 200 mu m. The pores formed by ice crystals transformed from cellular to lamellar, while the pores formed by fibers were aligned macro-channels, which were also in alignment with the lamellar pores. Keeping the initial slurry concentration constant and increasing the packing density of fibers, the volume fraction of macro-channels and open porosity increased, and the compressive strength decreased. Maintaining the packing density of fibers and increasing the initial slurry concentration, the pore sizes of lamellar pores and open porosity decreased, and the compressive strength increased. The results indicated that it was possible to manufacture porous CaSiO3 bioceramics with the macro-channels of 250-350 mu m, lamellae spacing of 50-100 mu m, open porosity of 71.12-83.94% and compressive strength of 0.87-3.59 MPa, indicating the suitability for tissue engineering. (C) 2013 Elsevier Ltd and Techna Group S.r.l. All rights reserved.