Valorization of glycerol through the production of biopolymers: The PHB case using Bacillus megaterium

被引:78
作者
Naranjo, Javier M. [1 ]
Posada, John A. [1 ]
Higuita, Juan C. [1 ]
Cardona, Carlos A. [1 ]
机构
[1] Univ Nacl Colombia, Inst Biotecnol & Agroind, Dept Ingn Quim, Manizales, Colombia
关键词
Bacillus megaterium; Glycerol; Adaptation; PHB bioproduction; Simulation process; POLYHYDROXYALKANOATE PRODUCTION; POLY(3-HYDROXYBUTYRATE); POLY-3-HYDROXYBUTYRATE; BIOSYNTHESIS; WHEY; SUGARCANE; RECOVERY; BACTERIA; ETHANOL; STRAIN;
D O I
10.1016/j.biortech.2013.01.129
中图分类号
S2 [农业工程];
学科分类号
0828 ;
摘要
In this work technical and economic analyses were performed to evaluate the glycerol transformation into Polyhydroxybutyrate using Bacillus megaterium. The production of PHB was compared using glycerol or glucose as substrates and similar yields were obtained. The total production costs for PHB generation with both substrates were estimated at an industrial scale. Compared to glucose, glycerol showed a 10% and 20% decrease in the PHB production costs using two different separation schemes respectively. Moreover, a 20% profit margin in the PHB sales price using glycerol as substrate resulted in a 166% valorization of crude glycerol. In this work, the feasibility of glycerol as feedstock for the production of PHB at laboratory (up to 60% PHB accumulation) and industrial (2.6US$/kgPHB) scales is demonstrated. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:38 / 44
页数:7
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