Three New ß-Resorcylic Acid Lactones from Paecilomyces sp SC0924

被引:25
作者
Xu Liangxiong [1 ]
Xue Jinghua [1 ]
Zou Yong [2 ]
He Shujie [2 ]
Wei Xiaoyi [1 ]
机构
[1] Chinese Acad Sci, S China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[2] Chinese Acad Sci, Guangzhou Inst Chem, Guangzhou 510650, Guangdong, Peoples R China
关键词
paecilomycins G-H; lactones; macrocycles; Paecilomyces sp; antifungal activity; FUNGUS; ZEARALENONE; MACROLIDES;
D O I
10.1002/cjoc.201200406
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Three new beta-resorcylic acid lactones (RALs), paecilomycins GI (13), and eight known compounds, aigialomycins BD (46), 1',2'-epoxy aigialomycin D (7), zearalenone (8), 7'-dehydrozearalenone (9), and trans-7',8'-dehydrozearalenol (10), antibiotic LL-Z1640-1 (11), were isolated from the mycelial solid culture of Paecilomyces sp. SC0924. Their structures were established by spectroscopic methods and chemical means. In an assessment of antifungal activity by the well plate diffusion method, five known RALs, 47 and 11 showed weak activities against Peronophythora litchii
引用
收藏
页码:1273 / 1277
页数:5
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