In-the-plane design of an off-axis ophthalmic adaptive optics system using toroidal mirrors

被引:48
作者
Liu, Zhuolin [1 ]
Kocaoglu, Omer P. [2 ]
Miller, Donald T. [1 ,2 ]
机构
[1] Indiana Univ, Program Vis Sci, Bloomington, IN 47405 USA
[2] Indiana Univ, Sch Optometry, Bloomington, IN 47405 USA
关键词
SCANNING LASER OPHTHALMOSCOPE; COHERENCE TOMOGRAPHY; CONE PHOTORECEPTORS; HIGH-RESOLUTION; DIMENSIONS; RETINA;
D O I
10.1364/BOE.4.003007
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Adaptive optics (AO) ophthalmoscopes have garnered increased clinical and scientific use for imaging the microscopic retina. Unlike conventional ophthalmoscopes, however, AO systems are commonly designed with spherical mirrors that must be used off-axis. This arrangement causes astigmatism to accumulate at the retina and pupil conjugate planes, degrading AO performance. To mitigate this effect and more fully tap the benefit of AO, we investigated a novel solution based on toroidal mirrors. Derived 2nd order analytic solutions along with commercial ray tracing predict performance benefit of toroidal mirrors for ophthalmoscopic use. For the Indiana AO ophthalmoscope, a minimum of three toroids is required to achieve performance criteria for retinal image quality, beam displacement, and beam ellipticity. Measurements with fabricated toroids and retinal imaging on subjects substantiate the theoretical predictions. Comparison to off-the-plane method is also presented. (C) 2013 Optical Society of America
引用
收藏
页码:3007 / 3029
页数:23
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