Spectral, XRD, SEM and biological properties of new mononuclear Schiff base transition metal complexes

被引：121

作者：

Khan, M. I. ^{[1
]}

Khan, Ayub ^{[1
]}

Hussain, Iqbal ^{[1
]}

Khan, Murad Ali ^{[1
]}

Gul, Saima ^{[1
]}

Iqbal, Mohammad ^{[2
]}

Inayat-Ur-Rahman ^{[3
]}

Khuda, Fazli ^{[4
]}

机构：

[1] Kohat Univ Sci & Technol, Dept Chem, Kohat 26000, Khyber Pakhtunk, Pakistan

[2] Univ Windsor, Dept Chem & Biochem, Windsor, ON N9B 3P4, Canada

[3] Gandhara Univ, Gandhara Coll Pharm, Peshawar, Khyber Pakhtunk, Pakistan

[4] Univ Peshawar, Dept Pharm, Peshawar, Khyber Pakhtunk, Pakistan

来源：

INORGANIC CHEMISTRY COMMUNICATIONS | 2013年 / 35卷

关键词：

Schiff base; Transition metal complexes; Anti-bacterial; Anti-fungal; Anti-leishmanial; ANTIMICROBIAL ACTIVITY; ELECTRONIC-SPECTRA; COPPER(II); REACTIVITY; CARBOXALDEHYDE; NICKEL(II); COBALT(II); DINUCLEAR; ZINC(II); NI(II);

D O I：

10.1016/j.inoche.2013.06.014

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Six new transition metal complexes derived from the reaction of 4(4-(dimethylamino) benzylideneamino) benzoic acid and Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) cations, were prepared, isolated and characterized by a range of spectral and analytical methods including UV/Vis, FT IR, NMR, MS, powder XRD, TGA and SEM. The complexes were formed with the deprotonation of the ligand and presented typical six-coordinated octahedral geometry. In addition, the biological activity was evaluated by conducting in vitro anti-bacterial, anti-fungal and anti-leishmanial screenings. All the complexes were found more active than the ligand, while complex 7 revealed biological significance. (C) 2013 Elsevier B.V. All rights reserved.

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页码：104 / 109

页数：6

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