Using the dynamic light-scattering method for the analysis of a blood-serum model solution

被引：3

作者：

Papok, I. M. ^{[1
]}

Petrova, G. P. ^{[1
]}

Anenkova, K. A. ^{[1
]}

Papish, E. A. ^{[1
]}

机构：

[1] Moscow MV Lomonosov State Univ, Fac Phys, Dept Mol Phys, Moscow 119991, Russia

来源：

MOSCOW UNIVERSITY PHYSICS BULLETIN | 2012年 / 67卷 / 05期

关键词：

bovine serum albumin; gamma globulin; blood-serum solution; photon correlation spectroscopy; dynamic light scattering; correlation function; mass diffusivity;

D O I：

10.3103/S0027134912050104

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

We used photon correlation spectroscopy to investigate various dynamic processes that occur in samples of a blood-serum solution. These processes were induced by directional changes of the surface charges of macromolecules and the concentration of the solution. We suggest that the obtained associations between the translational diffusion coefficient value (D (t) ) and the medium pH value, as well as the protein concentration value, indicate the possibility of using the dynamic light scattering method for the effective diagnosis of common diseases, including cardiovascular lesions and cancers.

引用

页码：452 / 456

页数：5

共 10 条

[1] Alberts B., 2017, Molecular Biology of the Cell
[2] Boiko A. V., 2005, 2 MOSK GOS U
[3] Brilliantov V. K., 1996, MOL DYNAMICS DISORDE
[4] Eskin V. E., 1986, Light Scattering by Polymer Solutions and Properties of Macromolecules
[5] Kammins G. Z., 1974, PHOTON CORRELATION L
[6] Pecora R., 1984, DYNAMIC LIGHT SCATTE
[7] Optical properties of solutions consisting of albumin and γ-globulin molecules in different ratio modeling blood serum
Petrova, G. P.
Boiko, A. V.
Fedorova, K. V.
Sergeeva, I. A.
Sokol, N. V.
Tichonova, T. N.
[J]. LASER PHYSICS, 2009, 19 (06) : 1303 - 1307
[8] Petrova G. P., 2009, OPTICAL SPECTRAL M 2
[9] Petrova G.P., 2008, OPTICAL SPECTRAL M 1
[10] PETROVA GP, 2000, BIOMED RADIOELEKTRON, P41

← 1 →