Ghrelin and eating disorders

被引:39
作者
Atalayer, Deniz [1 ,2 ]
Gibson, Charlisa [1 ]
Konopacka, Alexandra [1 ]
Geliebter, Allan [1 ,2 ,3 ]
机构
[1] St Lukes Roosevelt Hosp, Dept Med, New York Obes Res & Nutr Ctr, New York, NY 10025 USA
[2] Columbia Univ Coll Phys & Surg, Dept Psychiat, New York, NY 10032 USA
[3] Touro Coll, Dept Psychol, New York, NY USA
关键词
Anorexia nervosa; Bulimia nervosa; Binge eating disorder; Des-acyl ghrelin; Ghrelin; DES-ACYL GHRELIN; BODY-MASS-INDEX; FAMILY TRIOS ANALYSIS; Y GASTRIC BYPASS; PLASMA GHRELIN; ANOREXIA-NERVOSA; GROWTH-HORMONE; FOOD-INTAKE; BULIMIA-NERVOSA; CIRCULATING GHRELIN;
D O I
10.1016/j.pnpbp.2012.08.011
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
There is growing evidence supporting a multifactorial etiology that includes genetic, neurochemical, and physiological components for eating disorders above and beyond the more conventional theories based on psychological and sociocultural factors. Ghrelin is one of the key gut signals associated with appetite, and the only known circulating hormone that triggers a positive energy balance by stimulating food intake. This review summarizes recent findings and several conflicting reports on ghrelin in eating disorders. Understanding these findings and inconsistencies may help in developing new methods to prevent and treat patients with these disorders. Published by Elsevier Inc.
引用
收藏
页码:70 / 82
页数:13
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