Advances in liquid biopsy approaches for early detection and monitoring of cancer

被引：77

作者：

Babayan, Anna ^{[1
]}

Pantel, Klaus ^{[1
]}

机构：

[1] Univ Med Ctr Hamburg Eppendorf, Dept Tumor Biol, Martinistr 52, D-20246 Hamburg, Germany

来源：

GENOME MEDICINE | 2018年 / 10卷

关键词：

Liquid biopsy; Circulating tumor cells; ctDNA; Minimal residual disease; Early detection; Biomarker; CELL-FREE DNA; LUNG-CANCER; EVOLUTION; BLOOD;

D O I：

10.1186/s13073-018-0533-6

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Progress in sensitive analytical approaches has opened new avenues for the detection of cells or products such as circulating cell-free DNA released by tumors. These 'liquid biopsies' are being explored in clinical trials for early cancer detection, prediction of recurrent disease, and assessment of therapeutic resistance mechanisms.

引用

页数：3

共 11 条

[1] Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution [J].

Abbosh, Christopher ;

Birkbak, Nicolai J. ;

Wilson, Gareth A. ;

Jamal-Hanjani, Mariam ;

Constantin, Tudor ;

Salari, Raheleh ;

Le Quesne, John ;

Moore, David A. ;

Veeriah, Selvaraju ;

Rosenthal, Rachel ;

Marafioti, Teresa ;

Kirkizlar, Eser ;

Watkins, Thomas B. K. ;

McGranahan, Nicholas ;

Ward, Sophia ;

Martinson, Luke ;

Riley, Joan ;

Fraioli, Francesco ;

Al Bakir, Maise ;

Gronroos, Eva ;

Zambrana, Francisco ;

Endozo, Raymondo ;

Bi, Wenya Linda ;

Fennessy, Fiona M. ;

Sponer, Nicole ;

Johnson, Diana ;

Laycock, Joanne ;

Shafi, Seema ;

Czyzewska-Khan, Justyna ;

Rowan, Andrew ;

Chambers, Tim ;

Matthews, Nik ;

Turajlic, Samra ;

Hiley, Crispin ;

Lee, Siow Ming ;

Forster, Martin D. ;

Ahmad, Tanya ;

Falzon, Mary ;

Borg, Elaine ;

Lawrence, David ;

Hayward, Martin ;

Kolvekar, Shyam ;

Panagiotopoulos, Nikolaos ;

Janes, Sam M. ;

Thakrar, Ricky ;

Ahmed, Asia ;

Blackhall, Fiona ;

Summers, Yvonne ;

Hafez, Dina ;

Naik, Ashwini .

NATURE, 2017, 545 (7655) :446-+

[2] Liquid Biopsies, What We Do Not Know (Yet) [J].

Bardelli, Alberto ;

Pantel, Klaus .

CANCER CELL, 2017, 31 (02) :172-179

[3] Detecting Blood-Based Biomarkers in Metastatic Breast Cancer: A Systematic Review of Their Current Status and Clinical Utility [J].

Berghuis, A. M. Sofie ;

Koffijberg, Hendrik ;

Prakash, Jai ;

Terstappen, Leon W. M. M. ;

IJzerman, Maarten J. .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (02)

[4] Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling [J].

Chaudhuri, Aadel A. ;

Chabon, Jacob J. ;

Lovejoy, Alexander F. ;

Newman, Aaron M. ;

Stehr, Henning ;

Azad, Tej D. ;

Khodadoust, Michael S. ;

Esfahani, Mohammad Shahrokh ;

Liu, Chih Long ;

Zhou, Li ;

Scherer, Florian ;

Kurtz, David M. ;

Say, Carmen ;

Carter, Justin N. ;

Merriott, David J. ;

Dudley, Jonathan C. ;

Binkley, Michael S. ;

Modlin, Leslie ;

Padda, Sukhmani K. ;

Gensheimer, Michael F. ;

West, Robert B. ;

Shrager, Joseph B. ;

Neal, Joel W. ;

Wakelee, Heather A. ;

Loo, Billy W., Jr. ;

Alizadeh, Ash A. ;

Diehn, Maximilian .

CANCER DISCOVERY, 2017, 7 (12) :1394-1403

[5] Detection and localization of surgically resectable cancers with a multi-analyte blood test [J].

Cohen, Joshua D. ;

Li, Lu ;

Wang, Yuxuan ;

Thoburn, Christopher ;

Afsari, Bahman ;

Danilova, Ludmila ;

Douville, Christopher ;

Javed, Ammar A. ;

Wong, Fay ;

Mattox, Austin ;

Hruban, Ralph. H. ;

Wolfgang, Christopher L. ;

Goggins, Michael G. ;

Dal Molin, Marco ;

Wang, Tian-Li ;

Roden, Richard ;

Klein, Alison P. ;

Ptak, Janine ;

Dobbyn, Lisa ;

Schaefer, Joy ;

Silliman, Natalie ;

Popoli, Maria ;

Vogelstein, Joshua T. ;

Browne, James D. ;

Schoen, Robert E. ;

Brand, Randall E. ;

Tie, Jeanne ;

Gibbs, Peter ;

Wong, Hui-Li ;

Mansfield, Aaron S. ;

Jen, Jin ;

Hanash, Samir M. ;

Falconi, Massimo ;

Allen, Peter J. ;

Zhou, Shibin ;

Bettegowda, Chetan ;

Diaz, Luis A., Jr. ;

Tomasetti, Cristian ;

Kinzler, Kenneth W. ;

Vogelstein, Bert ;

Lennon, Anne Marie ;

Papadopoulos, Nickolas .

SCIENCE, 2018, 359 (6378) :926-+

[6] Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence [J].

Goh, Jian Yuan ;

Feng, Min ;

Wang, Wenyu ;

Oguz, Gokce ;

Yatim, Siti Maryam J. M. ;

Lee, Puay Leng ;

Bao, Yi ;

Lim, Tse Hui ;

Wang, Panpan ;

Tam, Wai Leong ;

Kodahl, Annette R. ;

Lyng, Maria B. ;

Sarma, Suman ;

Lin, Selena Y. ;

Lezhava, Alexander ;

Yap, Yoon Sim ;

Lim, Alvin S. T. ;

Hoon, Dave S. B. ;

Ditzel, Henrik J. ;

Lee, Soo Chin ;

Tan, Ern Yu ;

Yu, Qiang .

NATURE MEDICINE, 2017, 23 (11) :1319-+

[7] Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition [J].

Goodall, Jane ;

Mateo, Joaquin ;

Yuan, Wei ;

Mossop, Helen ;

Porta, Nuria ;

Miranda, Susana ;

Perez-Lopez, Raquel ;

Dolling, David ;

Robinson, Dan R. ;

Sandhu, Shahneen ;

Fowler, Gemma ;

Ebbs, Berni ;

Flohr, Penny ;

Seed, George ;

Rodrigues, Daniel Nava ;

Boysen, Gunther ;

Bertan, Claudia ;

Atkin, Mark ;

Clarke, Matthew ;

Crespo, Mateus ;

Figueiredo, Ines ;

Riisnaes, Ruth ;

Sumanasuriya, Semini ;

Rescigno, Pasquale ;

Zafeiriou, Zafeiris ;

Sharp, Adam ;

Tunariu, Nina ;

Bianchini, Diletta ;

Gillman, Alexa ;

Lord, Christopher J. ;

Hall, Emma ;

Chinnaiyan, Arul M. ;

Carreira, Suzanne ;

de Bono, Johann S. .

CANCER DISCOVERY, 2017, 7 (09) :1006-1017

[8] Circulating tumour cells in cancer patients: challenges and perspectives [J].

Pantel, Klaus ;

Alix-Panabieres, Catherine .

TRENDS IN MOLECULAR MEDICINE, 2010, 16 (09) :398-406

[9]

Siravegna G, 2015, NAT MED, V21, P795, DOI 10.1038/nm.3870

[10] Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer [J].

Tie, Jeanne ;

Wang, Yuxuan ;

Tomasetti, Cristian ;

Li, Lu ;

Springer, Simeon ;

Kinde, Isaac ;

Silliman, Natalie ;

Tacey, Mark ;

Wong, Hui-Li ;

Christie, Michael ;

Kosmider, Suzanne ;

Skinner, Iain ;

Wong, Rachel ;

Steel, Malcolm ;

Tran, Ben ;

Desai, Jayesh ;

Jones, Ian ;

Haydon, Andrew ;

Hayes, Theresa ;

Price, Tim J. ;

Strausberg, Robert L. ;

Diaz, Luis A., Jr. ;

Papadopoulos, Nickolas ;

Kinzler, Kenneth W. ;

Vogelstein, Bert ;

Gibbs, Peter .

SCIENCE TRANSLATIONAL MEDICINE, 2016, 8 (346)

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