A prospective comparison of the efficacy of 0.5% bupivacaine vs 0.75% ropivacaine in peribulbar anesthesia for vitreoretinal surgery

被引:8
作者
Jaichandran, V. V. [1 ]
Srinivasan, Sangeetha [2 ]
Raman, Sonali [1 ]
Jagadeesh, V [1 ]
Raman, Rajiv [3 ]
机构
[1] Sankara Nethralaya, Dept Anesthesiol, Chennai, Tamil Nadu, India
[2] Vis Res Fdn, Chennai, Tamil Nadu, India
[3] Shri Bhagwan Mahavir Vitreoretinal Serv, Chennai, Tamil Nadu, India
关键词
Anesthesia; bupivacaine; peribulbar; ropivacaine; vitreoretinal surgery; ANALGESIA;
D O I
10.4103/ijo.IJO_239_19
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To date, there is no information on the comparison of the effect of 0.5% bupivacaine with 0.75% ropivacaine solution for vitreoretinal surgery. The aim of the study was to compare the efficacy of 0.5% bupivacaine with 0.75% ropivacaine in peribulbar anesthesia for vitreoretinal surgery. This was a prospective randomized double-blinded observational study in a hospital setting. Sixty patients planned for vitreoretinal surgery were randomized into two groups based on the peribulbar injection administered either with 0.5% bupivacaine or 0.75% ropivacaine solution, as Group B (n = 30) and Group R (n = 30), respectively. Time of onset of analgesia, akinesia, and the need for supplemental anesthesia were noted. Student's t-test or Mann-Whitney U test were used for comparing continuous variables and Chi-square or a Fischer exact test were used as appropriate for comparing two proportions. Results: The patients in Group R showed an earlier onset of both, analgesia (1.97 min vs. 2.10 min, P = 0.002) and akinesia (2.77 min vs. 4.20 min, P < 0.001) compared with the patients in Group B. The efficacy of the block attained was Grade 5 (adequate anesthesia and akinesia without supplementation) in about 97% of the patients in Group R while only 90% in Group B. However, the differences between the groups for the efficacy of the block were not statistically significant (P = 0.301) neither for Grades 5 nor for Grade 4 and 3 (P = 1.00 for both). The onset of postoperative pain was similar for both groups (P = 1.00). Conclusion: We concluded that 0.75% ropivacaine is a better choice of local anesthetic solution for patients undergoing primary vitreoretinal surgery compared with 0.5% bupivacaine.
引用
收藏
页码:153 / 156
页数:4
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