Proposal of an algorithm for analysis of bone demineralization using synchrotron radiation X-ray μCT images

被引:0
作者
Gomes Pinheiro, Christiano Jorge [1 ]
de Moura Meneses, Anderson Alvarenga [1 ]
Braz, Delson [1 ]
de Oliveira, Luis Fernando [1 ]
Rodrigues Barroso, Regina Cely [1 ]
机构
[1] Alto Univ, Dept Quim & Fis, UFES, Alegre, ES, Brazil
关键词
Synchrotron radiation; X-Ray; Micro-computed tomography; Topology; Connectivity; CANCELLOUS BONE; COMPUTED-TOMOGRAPHY; QUANTIFICATION; ARCHITECTURE;
D O I
10.1016/j.radphyschem.2013.01.001
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Research on radiation effects on bony tissue, osteoporosis and other diseases demands the assessment of bone structures. Synchrotron Radiation (SR) X-ray micro-Computed Tomography (mu CT) is an imaging technique that allows the investigation of such structures in the micrometer level. With the high coherence as well as the monochromaticity of the SR beam, it is possible to assess pathological conditions in those structures accurately, providing quantitative information for decision making. Topology and Histomorphometry provide parameters which describe the relationships between pores, canals and the connectivity in structures. Thus, with periodical assessment of the bone structure by SR-mu CT imaging, it is possible to verify the evolution of a disease or the impact of a treatment. In the present summary we describe the application of Topology concepts for quantitative assessment of bone structures in the analysis of SR-mu CT images acquired at the Elettra Laboratory (Trieste, Italy). (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:258 / 260
页数:3
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