Diagnostic value of FDG-PET in recurrent colorectal carcinoma: A meta-analysis

被引：26
作者：
Zhang, Chenpeng [1 ]
Chen, Yumei [1 ]
Xue, Huiping [2 ]
Zheng, Ping [3 ]
Tong, Jinlu [2 ]
Liu, Jianjun [1 ]
Sun, Xiaoguang [1 ]
Huang, Gang [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Dept Nucl Med, Renji Hosp, Sch Med, Shanghai 200127, Peoples R China
[2] Renji Hosp, Shanghai Inst Gastrointestinal Dis, Dept Gastroenterol, Shanghai, Peoples R China
[3] Shanghai Fist Peoples Hosp, Dept Gastroenterol, Shanghai, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CANCER | 2009年 / 124卷 / 01期
关键词：
meta-analysis; colorectal; tomography; emission-computed; recurrence; POSITRON-EMISSION-TOMOGRAPHY; CARCINOEMBRYONIC ANTIGEN; F-18; FLUORODEOXYGLUCOSE; RECTAL-CANCER; COMPUTED-TOMOGRAPHY; LIVER METASTASES; HEPATIC METASTASES; DECISION-ANALYSIS; LOCAL RECURRENCE; CLINICAL-VALUE;
D O I：
10.1002/ijc.23926
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Accurate detection of recurrent colorectal carcinoma remains a diagnostic challenge. The purposes of this study were to evaluate the diagnostic value of Positron emission tomography (PET) using fluor-18-deoxyglucose (FDG) in recurrent colorectal carcinoma with a meta-analysis. All the published studies in English relating the diagnostic value of FDG-PET in the detection of recurrent colorectal carcinoma were collected. Methodological quality of the included studies was evaluated. Pooled sensitivity, specificity and diagnostic odds ratio and SROC (summary receiver operating characteristic curves) were obtained by the statistical software. Twenty-seven studies were included in the meta-analysis. The pooled sensitivity and specificity for FDG-PET detecting distant metastasis or whole body involvement in recurrent colorectal carcinoma were 0.91 (95% CI 0.88-0.92) and 0.83 (95% CI 0.79-0.87), respectively. The pooled sensitivity and specificity for FDG-PET detecting hepatic metastasis were (1.97 (95% CI 0.95-0.98) and 0.98 (95% CI 0.97-0.99). The pooled sensitivity and specificity for pelvic metastasis or local regional recurrence were 0.94 (95% CI 0.91-0.97) anti 0.94 (95% CI 0.92-0.96). FDG-PET is valuable for the assessment of recurrent colorectal carcinoma. (C) 2008 Wiley-Liss, Inc.
引用
收藏
页码：167 / 173
页数：7
相关论文
共 45 条
[1]   The impact of FDG-PET on the management algorithm for recurrent colorectal cancer [J].
Arulampalam, T ;
Costa, D ;
Visvikis, D ;
Boulos, P ;
Taylor, I ;
Ell, P .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE, 2001, 28 (12) :1758-1765
[2]  
Bast RC, 1996, J CLIN ONCOL, V14, P2843
[3]   CLINICAL-VALUE OF WHOLE-BODY POSITRON EMISSION TOMOGRAPHY WITH [F-18] FLUORODEOXYGLUCOSE IN RECURRENT COLORECTAL-CANCER [J].
BEETS, G ;
PENNINCKX, F ;
SCHIEPERS, C ;
FILEZ, L ;
MORTELMANS, L ;
KERREMANS, R ;
AERTS, R ;
DEROO, M .
BRITISH JOURNAL OF SURGERY, 1994, 81 (11) :1666-1670
[4]   Role of multidetector CT and FDG-PET/CT in the diagnosis of local and distant recurrence of resected rectal cancer [J].
Bellomi M. ;
Rizzo S. ;
Travaini L.L. ;
Bazzi L. ;
Trifirò G. ;
Zampino M.G. ;
Radice D. ;
Paganelli G. .
La radiologia medica, 2007, 112 (5) :681-690
[5]   Colorectal liver metastases: CT, MR imaging, and PET for diagnosis - Meta-analysis [J].
Bipat, S ;
van Leeuwen, MS ;
Comans, EFI ;
Pijl, MEJ ;
Bossuyt, PMM ;
Zwinderman, AH ;
Stoker, J .
RADIOLOGY, 2005, 237 (01) :123-131
[6]  
Delbeke D, 1997, J NUCL MED, V38, P1196
[7]   Colorectal cancer surveillance: 2005 update of an American Society of Clinical Oncology practice guideline [J].
Desch, CE ;
Benson, A ;
Somerfield, MR ;
Flynn, PJ ;
Krause, C ;
Loprinzi, CL ;
Minsky, BD ;
Pfister, DG ;
Virgo, KS ;
Petrelli, NJ .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (33) :8512-8519
[8]   Detection of recurrence in patients with rectal cancer: PET/CT after abdominoperineal or anterior resection [J].
Even-Sapir, E ;
Parag, Y ;
Lerman, H ;
Gutman, M ;
Levine, C ;
Rabau, M ;
Figer, A ;
Metser, U .
RADIOLOGY, 2004, 232 (03) :815-822
[9]   Five-year survival after resection of hepatic metastases from colorectal cancer in patients screened by positron emission tomography with F-18 fluorodeoxyglucose (FDG-PET) [J].
Fernandez, FG ;
Drebin, JA ;
Linehan, DC ;
Dehdashti, F ;
Siegel, BA ;
Strasberg, SM .
ANNALS OF SURGERY, 2004, 240 (03) :438-447
[10]   Unexplained rising carcinoembryonic antigen (CEA) in the postoperative surveillance of colorectal cancer: the utility of positron emission tomography (PET) [J].
Flamen, P ;
Hoekstra, OS ;
Homans, F ;
Van Cutsem, E ;
Maes, A ;
Stroobants, S ;
Peeters, M ;
Penninckx, F ;
Filez, L ;
Bleichrodt, RP ;
Mortelmans, L .
EUROPEAN JOURNAL OF CANCER, 2001, 37 (07) :862-869
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