Circadian rhythms of histatin 1, histatin 3, histatin 5, statherin and uric acid in whole human saliva secretion

被引：25

作者：

Castagnola, M

Cabras, T

Denotti, G

Fadda, MB

Gambarini, G

Lupi, A

Manca, I

Onnis, G

Piras, V

Soro, V

Tambaro, S

Messana, I

机构：

[1] Catholic Univ, Fac Med, Inst Biochem & Clin Biochem, Rome, Italy

[2] CNR, Ctr Chem Receptors & Biol Act Mol, Rome, Italy

[3] Univ Cagliari, Dept Sci Appl Biosyst, Cagliari, Italy

[4] Univ Cagliari, Dept Odontostomatol, Cagliari, Italy

[5] Univ Roma La Sapienza, Fac Med, Inst Odontioatr Clin, Rome, Italy

来源：

BIOLOGICAL RHYTHM RESEARCH | 2002年 / 33卷 / 02期

关键词：

human saliva; peptides; histatin; statherin; circadian rhythms; urate;

D O I：

10.1076/brhm.33.2.213.1314

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The circadian rhythms of histatins 1, 3, 5, of statherin and uric acid were investigated in whole human saliva. Histatins showed a rhythm approximately synchronous with salivary flow rate (acrophase around 5 pm), the higher amplitude pertaining to histatin 1 (about 50% of the mesor). Uric acid showed a large rhythm asynchronous with flow rate and histatin concentrations (4.4 +/- 1.4 am). Statherin did not show a significant circadian rhythm on five of six volunteers. This finding confirms that the secretion route of statherin is different from that of histatins.

引用

页码：213 / 222

页数：10

共 33 条

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