A New C-Glycosylflavone from the Rhizomes of Cyperus rotundus

被引:2
作者
Zhou, Zhongliu [1 ]
Zhang, Tianzhu [1 ]
Xiao, Hongping [1 ]
Zhou, Xia [1 ]
Wu, Huiyan [1 ]
机构
[1] Lingnan Normal Univ, Sch Chem & Chem Engn, Zhanjiang 524048, Peoples R China
基金
中国国家自然科学基金;
关键词
Cyperus rotundus; flavonoid; macrophage respiratory burst; MACROPHAGES; FLAVONOIDS; GLYCOSIDES; BURST;
D O I
10.1007/s10600-015-1374-9
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new flavone C-glycoside, 5,7-dihydroxy-4'-methoxy-8-C-[2aEuro(3)-(2aEuro(3)aEuro(2)-methylbutyryl)]-beta-D-glucopyranosyl flavone (1), was isolated from the rhizomes of Cyperus rotundus. Its chemical structure was elucidated on the basis of UV, IR, MS, and NMR spectroscopic analyses. Compound 1 showed moderate inhibitory activity against MRB in the test, with an IC50 value of approximately 56.03 mu M.
引用
收藏
页码:640 / 642
页数:3
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