Negative pressure wound therapy technologies for chronic wound care in the home setting: A systematic review

被引:8
作者
Rhee, Susan M. [1 ]
Valle, M. Frances [2 ]
Wilson, Lisa M. [3 ]
Lazarus, Gerald [4 ]
Zenilman, Jonathan M. [1 ]
Robinson, Karen A. [5 ]
机构
[1] Johns Hopkins Univ, Div Infect Dis, Sch Med, Johns Hopkins Bayview Med Ctr, Baltimore, MD 21218 USA
[2] Univ Maryland, Sch Nursing, Dept Org Syst & Adult Hlth, College Pk, MD USA
[3] Johns Hopkins Univ Bloomberg, Sch Publ Hlth, Dept Hlth Policy & Management, Baltimore, MD USA
[4] Johns Hopkins Univ, Sch Med, Dept Dermatol, Baltimore, MD 21218 USA
[5] Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA
关键词
EXTRACELLULAR-MATRIX; DERMAL FIBROBLASTS; SKIN; REPAIR; ANGIOGENESIS; CONTRACTION; ELASTICITY; EXPRESSION; SCAFFOLDS; RESPONSES;
D O I
10.1111/wrr.12295
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The use of negative pressure wound therapy (NPWT) is increasing in both the inpatient and outpatient settings. We conducted a systematic review on the efficacy and safety of NPWT for the treatment of chronic wounds in the home setting. We searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and the Cumulative Index to Nursing and Allied Health Literature, up to June 2014. Two independent reviewers screened search results. Seven studies met our criteria for inclusion. Six of the studies compared NPWT devices to other wound care methods and one study compared two different NPWT technologies. Data were limited by variability in the types of comparator groups, methodological limitations, and poor reporting of outcomes. We were unable to draw conclusions about the efficacy or safety of NPWT for the treatment of chronic wounds in the home setting due to the insufficient evidence. Consensus is needed on the methods of conducting and reporting wound care research so that future studies are able inform decisions about the use of NPWT in the home environment for chronic wounds.
引用
收藏
页码:506 / 517
页数:12
相关论文
共 43 条
[1]   Skin scarring [J].
Bayat, A ;
McGrouther, DA ;
Ferguson, MWJ .
BRITISH MEDICAL JOURNAL, 2003, 326 (7380) :88-92
[2]   Responses of fibroblasts to anchorage of dorsal extracellular matrix receptors [J].
Beningo, KA ;
Dembo, M ;
Wang, YI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (52) :18024-18029
[3]  
Bloch W, 2000, FASEB J, V14, P2373
[4]   Impaired wound contraction in stromelysin-1-deficient mice [J].
Bullard, KM ;
Lund, L ;
Mudgett, JS ;
Mellin, TN ;
Hunt, TK ;
Murphy, B ;
Ronan, J ;
Werb, Z ;
Banda, MJ .
ANNALS OF SURGERY, 1999, 230 (02) :260-265
[5]   Wound healing: An overview of acute, fibrotic and delayed healing [J].
Diegelmann, RF ;
Evans, MC .
FRONTIERS IN BIOSCIENCE-LANDMARK, 2004, 9 :283-289
[6]   Oncostatin M decreases interleukin-1 ß secretion by human synovial fibroblasts and attenuates an acute inflammatory reaction in vivo [J].
Dumas, Aline ;
Lagarde, Stephanie ;
Laflamme, Cynthia ;
Pouliot, Marc .
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2012, 16 (06) :1274-1285
[7]   Inflammation in wound repair: Molecular and cellular mechanisms [J].
Eming, Sabine A. ;
Krieg, Thomas ;
Davidson, Jeffrey M. .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2007, 127 (03) :514-525
[8]   Matrix elasticity directs stem cell lineage specification [J].
Engler, Adam J. ;
Sen, Shamik ;
Sweeney, H. Lee ;
Discher, Dennis E. .
CELL, 2006, 126 (04) :677-689
[9]   Optical coherence tomography in dermatology: technical and clinical aspects [J].
Gambichler, Thilo ;
Jaedicke, Volker ;
Terras, Sarah .
ARCHIVES OF DERMATOLOGICAL RESEARCH, 2011, 303 (07) :457-473
[10]   Scarless skin repair in immunodeficient mice [J].
Gawronska-Kozak, Barbara ;
Bogacki, Marek ;
Rim, Jong-Seop ;
Monroe, W. Todd ;
Manuel, Jessica A. .
WOUND REPAIR AND REGENERATION, 2006, 14 (03) :265-276