Self-Immolative Linkers as Caps for the Design of Gated Silica Mesoporous Supports

被引：11

作者：

Alberto Juarez, L. ^{[1
,2
]}

Anon, Elena ^{[1
,2
]}

Gimenez, Cristina ^{[1
,3
,4
]}

Sancenon, Felix ^{[1
,3
,4
]}

Martinez-Manez, Ramon ^{[1
,3
,4
]}

Costero, Ana M. ^{[1
,2
,4
]}

Gavina, Pablo ^{[1
,2
,4
]}

Parra, Margarita ^{[1
,2
,4
]}

Bernardos, Andrea ^{[1
,3
,4
]}

机构：

[1] Inst Interuniv Invest Reconocimiento Mol & Desarr, Valencia, Spain

[2] Univ Valencia, Dept Quim Organ, Doctor Moliner 50, E-46100 Valencia, Spain

[3] Univ Politecn Valencia, Dept Quim, Camino Vera S-N, E-46022 Valencia, Spain

[4] CIBER BBN, Zaragoza, Spain

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2016年 / 22卷 / 40期

关键词：

dyes/pigments; mesoporous materials; molecular devices; pH-responsive systems; silica; CONTROLLED-RELEASE; DELIVERY-SYSTEMS; NANOPARTICLES; ACTIVATION; DNA; POLYMERS; SPACER; LIGHT;

D O I：

10.1002/chem.201602126

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new hybrid material based on sulforhodamine-B dye-loaded silica mesoporous nanoparticles capped with a self-immolative gate has been synthesized and characterized. The gated material's controlled release behavior is monitored under different pH conditions. Under acidic and neutral conditions, a low level of dye release is detected. However, at slightly basic pH, significant dye release occurs owing to deprotonation of the phenol moiety in the capping molecule, which results in its disassembly.

引用

页码：14126 / 14130

页数：5

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