Type D Personality as a Cardiovascular Risk Marker in the General Population: Results from the Gutenberg Health Study

被引:55
作者
Beutel, M. E. [1 ]
Wiltink, J. [1 ]
Till, Y. [1 ,2 ]
Wild, P. S. [2 ]
Muenzel, T. [2 ]
Ojeda, F. M. [2 ]
Zeller, T. [2 ]
Schnabel, R. B. [2 ]
Lackner, K. [3 ]
Blettner, M. [4 ]
Zwiener, I. [4 ]
Michal, M. [1 ]
机构
[1] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Psychosomat Med & Psychotherapy, DE-55131 Mainz, Germany
[2] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Dept Med 2, DE-55131 Mainz, Germany
[3] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Clin Chem & Lab Med, DE-55131 Mainz, Germany
[4] Johannes Gutenberg Univ Mainz, Univ Med Ctr, Inst Med Biostat Epidemiol & Informat, DE-55131 Mainz, Germany
关键词
Type D personality; Depression; Anxiety; Coronary heart disease; Inflammation; Endothelial function; Lifestyle; ACUTE CORONARY SYNDROME; CHRONIC HEART-FAILURE; MAJOR DEPRESSIVE DISORDER; MYOCARDIAL-INFARCTION; NEGATIVE AFFECTIVITY; SOCIAL INHIBITION; HOSPITAL ANXIETY; DISEASE; SYMPTOMS; DEPERSONALIZATION;
D O I
10.1159/000331776
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Type D personality is considered as an independent risk factor for morbidity and mortality in cardiovascular patients and a vulnerability factor for distress in the general population. Because representative community studies are rare, we sought to determine the prevalence of type D personality and its relationship with demographic characteristics, different features of mental disorders, cardiovascular risk factors, health behavior, endothelial function and cardiovascular biomarkers in the general population. Methods: The prevalence of type D personality and its correlates were analyzed cross-sectionally in a population-based sample of 5,000 Mid-Europeans aged 35-74 years from the Gutenberg Health Study. Results: The prevalence of type D personality was 22.2% without remarkable differences in sex distribution. Type D subjects were characterized by lower socioeconomic status, lack of a partnership, increased depression, anxiety, depersonalization and health care utilization. Despite its strong association with mental disorders, type D personality emerged as psychometrically distinct. Although type D personality was independently associated with coronary heart disease (OR = 1.54, p = 0.044), no associations with traditional cardiovascular risk factors were found independently from depression or anxiety. Conclusions: Although type D personality is strongly associated with depression, anxiety, impaired mental and somatic health status, and increased health care utilization, the type D construct seems to comprise dysfunctional personality patterns not covered by depression and anxiety scales. Beyond these associations, the pathways of the cardiotoxic impact of type D personality remain to be elucidated. There is a need for prospective population studies on potential links between type D personality and cardiac disease. Copyright (C) 2012 S. Karger AG, Basel
引用
收藏
页码:108 / 117
页数:10
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