Occurrence of dyslipidemia in spontaneous intracerebral hemorrhage

Background: Dyslipidemia, mainly hypocholesterolemia is considered to be a risk factor (RF) for spontaneous intracerebral hemorrhage (SICH). The aim of our study was to assess its role in our SICH patients. Methods: In a hospital-based cross-section study, laboratory assessments of total cholesterol (TC), triglycerides (TG), high-density cholesterol (HDL-C) and low-density cholesterol (LDL-C) plasma levels were performed in 80 SICH patients without vascular malformation and in a control group (CG) of 80 age- and sex-matched patients with low back pain. All patients were treated at the Departments of Neurology and Neurosurgery, University Hospital, Olomouc, Czech Republic. Two-sample t-test and Mann-Whitney test were applied when assessing statistical significance. Results: The following mean lipid plasma levels were found in SICH patients versus CG subjects (in mmol/L): TC, 5.89 vs. 5.48 (p = 0.007); TG, 1.31 vs. 2.10 (p < 0.0001); HDL-C, 1.58 vs. 1.33 (p = 0.0001); LDL-C, 3.70 vs. 3.18 (p = 0.0004). Conclusions: TC and LDL-C plasma levels were higher in SICH patients in the Olomouc region of the Czech Republic.