Plasmon-Enhanced Whispering Gallery Mode Biosensing

被引：0

作者：

Vollmer, Frank ^{[1
]}

机构：

[1] Max Planck Inst Sci Light, D-91058 Erlangen, Germany

来源：

2012 PHOTONICS GLOBAL CONFERENCE (PGC) | 2012年

关键词：

enhancement; optical microcavity; whispering gallery mode; label-free biosensing; optical trapping;

D O I：

暂无

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Whispering gallery mode (WGM) biosensors derive their unprecedented sensitivity for label-free detection of biomolecules from the high-quality (Q) factor of an optical resonance phenomenon. Plasmonic excitations in metal nanostructures which are able to localize the WGM field at the target binding site can further enhance sensitivity by local electric field amplification. Random nanoparticle layers and nanopost antennas are investigated for this purpose, and an efficiency parameter is introduced to quantitate the local field overlap with analyte molecules, a pre-requisite for single molecule detection.

引用

页数：3

共 4 条

[1]

Kim Kyujung, ACS NANO

[2] Ultrasensitive detection of a protein by optical trapping in a photonic-plasmonic microcavity [J].

Santiago-Cordoba, Miguel A. ;

Cetinkaya, Murat ;

Boriskina, Svetlana V. ;

Vollmer, Frank ;

Demirel, Melik C. .

JOURNAL OF BIOPHOTONICS, 2012, 5 (8-9) :629-638

[3] Nanoparticle-based protein detection by optical shift of a resonant microcavity [J].

Santiago-Cordoba, Miguel A. ;

Boriskina, Svetlana V. ;

Vollmer, Frank ;

Demirel, Melik C. .

APPLIED PHYSICS LETTERS, 2011, 99 (07)

[4] Whispering-gallery-mode biosensing: label-free detection down to single molecules [J].

Vollmer, Frank ;

Arnold, Stephen .

NATURE METHODS, 2008, 5 (07) :591-596

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