Water-Soluble Triscyclometalated Organoiridium Complex: Phosphorescent Nanoparticle Formation, Nonlinear Optics, and Application for Cell Imaging

被引：35
作者：
Fan, Yuanpeng [1 ,2 ]
Zhao, Jingyi [3 ,4 ]
Yan, Qifan [1 ,2 ]
Chen, Peng R. [3 ]
Zhao, Dahui [1 ,2 ]
机构：
[1] Peking Univ, Dept Appl Chem, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China
[2] Peking Univ, Coll Chem, Minist Educ, Key Lab Polymer Chem & Phys, Beijing 100871, Peoples R China
[3] Peking Univ, Peking Tsinghua Ctr Life Sci, Beijing Natl Lab Mol Sci, Synthet & Funct Biomol Ctr,Dept Chem Biol, Beijing 100871, Peoples R China
[4] Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Lab Chem Genom, Shenzhen 518055, Peoples R China
来源：
ACS APPLIED MATERIALS & INTERFACES | 2014年 / 6卷 / 05期
基金：
中国国家自然科学基金;
关键词：
triscyclometalated iridium; water solubility; phosphorescent nanoparticles; phosphorescence cell imaging; multiphoton excitation phosphorescence; HYPERBRANCHED CONJUGATED POLYELECTROLYTE; ENERGY-TRANSFER PROPERTIES; IRIDIUM(III) COMPLEX; 2-PHOTON FLUORESCENCE; POLYMER NANOPARTICLES; 3-PHOTON ABSORPTION; LIVING CELLS; PROBE; DELIVERY; PHOTOPHYSICS;
D O I：
10.1021/am500549y
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Two water-soluble triscyclometalated organoiridium complexes, 1 and 2, with polar side chains that form nanoparticles emitting bright-red phosphorescence in water were synthesized. The optimal emitting properties are related to both the triscyclometalated structure and nanoparticle-forming ability in aqueous solution. Nonlinear optical properties are also observed with the nanoparticles. Because of their proper cellular uptake in addition to high emission brightness and effective two-photon absorbing ability, cell imaging can be achieved with nanoparticles of 2 bearing quaternary ammonium side chains at ultra-low effective concentrations using NIR incident light via the multiphoton excitation phosphorescence process.
引用
收藏
页码：3122 / 3131
页数：10
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