G-quadruplex unfolding in higher-order DNA structures

被引：6
|
作者：
Fotticchia, Iolanda [1 ]
Giancola, Concetta [2 ]
Petraccone, Luigi [3 ]
机构：
[1] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Fisciano, SA, Italy
[2] Univ Naples Federico II, Dipartimento Farm, I-80131 Naples, Italy
[3] Univ Naples Federico II, Dipartimento Sci Chim, I-80126 Naples, Italy
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 82期
关键词：
HUMAN TELOMERIC DNA; PROMOTER; STABILITY; KINETICS;
D O I：
10.1039/c3cc44560g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
G-quadruplex unfolding within a sequence of two quadruplex units was characterized by gel electrophoresis, calorimetry and spectroscopy. The obtained results suggest that the kinetics and thermodynamics of the individual quadruplex unfolding are affected by its interaction with other DNA secondary structural elements.
引用
收藏
页码：9488 / 9490
页数：3
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