Platelet Transfusion Therapy

被引:30
作者
Thiagarajan, Perumal [1 ,2 ]
Afshar-Kharghan, Vahid [3 ]
机构
[1] Baylor Coll Med, Michael E DeBakey Vet Affairs Med Ctr, Dept Pathol, Houston, TX 77030 USA
[2] Baylor Coll Med, Michael E DeBakey Vet Affairs Med Ctr, Dept Med, Houston, TX 77030 USA
[3] MD Anderson Canc Ctr, Sect Benign Hematol, Houston, TX 77030 USA
关键词
Platelet transfusion; Alloimmunization; Transfusion triggers; Pathogen reduction; PATHOGEN INACTIVATION; CROSS-MATCH; APHERESIS PLATELETS; BLEEDING DIATHESIS; IN-VITRO; PHOSPHATIDYLSERINE; INCREMENTS; ALLOIMMUNIZATION; THROMBOCYTOPENIA; PERMEABILITY;
D O I
10.1016/j.hoc.2013.03.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Platelet transfusion therapy has become an integral part of the treatment of patients with hematological and solid tumor malignancy receiving chemotherapy. Since its introduction almost 60 years ago, several advances and refinements have been introduced in the collection, storage, and administration to improve the safety and efficacy of platelet transfusion. This review summarizes the current practice and clinical approach to patients with thrombocytopenia. Existing evidence-based guidelines for appropriate platelet transfusion is reviewed.
引用
收藏
页码:629 / +
页数:16
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