BACKGROUND: Angiosarcoma is an aggressive, malignant neoplasm of vascular or lymphatic origin. Herpes virus 8 (HHV-8) is a member of the herpes family with a tropism for endothelial cells and it has been proven to induce vascular neoplasms, such as Kaposi's sarcoma. The role of HHV-8 in the pathogenesis of angiosarcoma has not been well defined. OBJECTIVE: To investigate the relationship between the presence of HHV-8 and angiosarcoma. METHODS: In this study, the team investigated the relationship between the presence of HHV-8, as determined by polymerase chain reaction, and angiosarcoma, using samples from patients with epidemic Kaposi's sarcoma as controls. RESULTS: While all control cases with epidemic Kaposi's sarcoma were positive for HHV-8, none of the angiosarcoma cases was. CONCLUSION: These findings support most previous studies that found no association between HHV-8 and angiosarcoma.
机构:
Institute of Social and Preventive Medicine (ISPM), University of Bern, BernInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Rohner E.
Wyss N.
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Institute of Social and Preventive Medicine (ISPM), University of Bern, BernInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Wyss N.
Trelle S.
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机构:
Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern
CTU Bern, Department of Clinical Research, University of Bern, BernInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Trelle S.
Mbulaiteye S.M.
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机构:
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MDInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Mbulaiteye S.M.
Egger M.
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机构:
Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Centre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape TownInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Egger M.
Novak U.
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机构:
Department of Medical Oncology, University Hospital, BernInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Novak U.
Zwahlen M.
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机构:
Institute of Social and Preventive Medicine (ISPM), University of Bern, BernInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
Zwahlen M.
Bohlius J.
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机构:
Institute of Social and Preventive Medicine (ISPM), University of Bern, BernInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern
机构:Tumaini Univ, Sch Med, Kilimanjaro Christian Med Ctr, RDTC, Moshi, Tanzania
Wamburu, G.
Masenga, E. J.
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机构:Tumaini Univ, Sch Med, Kilimanjaro Christian Med Ctr, RDTC, Moshi, Tanzania
Masenga, E. J.
Moshi, E. Z.
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机构:Tumaini Univ, Sch Med, Kilimanjaro Christian Med Ctr, RDTC, Moshi, Tanzania
Moshi, E. Z.
Schmid-Grendelmeier, P.
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机构:Tumaini Univ, Sch Med, Kilimanjaro Christian Med Ctr, RDTC, Moshi, Tanzania
Schmid-Grendelmeier, P.
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机构:
Kempf, W.
Orfanos, C. E.
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h-index: 0
机构:
Tumaini Univ, Sch Med, Kilimanjaro Christian Med Ctr, RDTC, Moshi, TanzaniaTumaini Univ, Sch Med, Kilimanjaro Christian Med Ctr, RDTC, Moshi, Tanzania
机构:
Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
Lopes, Amanda de O.
Lima, Lyana R. P.
论文数: 0引用数: 0
h-index: 0
机构:
Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
Lima, Lyana R. P.
Tozetto-Mendoza, Tania R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Sao Paulo, Inst Med Trop Sao Paulo, Lab Virol, LIM52, Sao Paulo, SP, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
Tozetto-Mendoza, Tania R.
Martinelli, Katrini G.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Fed Espirito Santo, Dept Med Social, Vitoria, ES, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
Martinelli, Katrini G.
Morgado, Mariza G.
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h-index: 0
机构:
Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab AIDS & Imunol Mol, Rio De Janeiro, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
Morgado, Mariza G.
Pilotto, Jose H.
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机构:
Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab AIDS & Imunol Mol, Rio De Janeiro, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
Pilotto, Jose H.
de Paula, Vanessa S.
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h-index: 0
机构:
Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, BrazilFundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Virol Mol, 4365 Brazil Ave, Manguinho, RJ, Brazil
机构:
Inst Pasteur, Dept Virol, URA CNRS 3015, Unite Epidemiol & Physiopathol Virus Oncogenes, F-75724 Paris 15, FranceInst Pasteur, Dept Virol, URA CNRS 3015, Unite Epidemiol & Physiopathol Virus Oncogenes, F-75724 Paris 15, France
Gessain, Antoine
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE,
2008,
192
(06):
: 1189
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1204