Fluid-structure interaction of blood flow around a vein valve

被引:24
作者
Hajati, Zahra [1 ]
Moghanlou, Farhad Sadegh [1 ]
Vajdi, Mohammad [1 ]
Razavi, Seyed Esmail [2 ]
Matin, Somaieh [3 ]
机构
[1] Univ Mohaghegh Ardabili, Fac Engn, Ardebil, Iran
[2] Univ Tabriz, Fac Mech Engn, Tabriz, Iran
[3] Ardabil Univ Med Sci, Dept Internal Med, Ardebil, Iran
关键词
Venous valve; Blood flow; Fluid-structure interaction; Numerical method; WALL SHEAR-STRESS; ELASTIC COMPRESSION; DEEP; CLOSURE;
D O I
10.34172/bi.2020.21
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction: Venous valves are a type of one-way valves which conduct blood flow toward the heart and prevent its backflow. Any malfunction of these organs may cause serious problems in the circulatory system. Numerical simulation can give us detailed information and point to point data such as velocity, wall shear stress, and von Mises stress from veins with small diameters, as obtaining such data is almost impossible using current medical devices. Having detailed information about fluid flow and valves' function can help the treatment of the related diseases. Methods: In the present work, the blood flow through a venous valve considering the flexibility of the vein wall and valve leaflets is investigated numerically. The governing equations of fluid flow and solid domain are discretized and solved by the Galerkin finite element method. Results: The obtained results showed that the blood velocity increases from inlet to the leaflets and then decreases passing behind the valve. A pair of vortices and the trapped region was observed just behind the valves. These regions have low shear stresses and are capable of sediment formation. Conclusion: The von Mises stress which is a criterion for the breakdown of solid materials was obtained. It was also observed that a maximum value occurred at the bottom of the leaflets.
引用
收藏
页码:169 / 175
页数:7
相关论文
共 36 条
[1]   Using Discrete Multi-Physics for studying the dynamics of emboli in flexible venous valves [J].
Ariane, M. ;
Vigolo, D. ;
Brill, A. ;
Nash, F. G. B. ;
Barigou, M. ;
Alexiadis, A. .
COMPUTERS & FLUIDS, 2018, 166 :57-63
[2]   Modelling and simulation of flow and agglomeration in deep veins valves using discrete multi physics [J].
Ariane, M. ;
Wen, W. ;
Vigolo, D. ;
Brill, A. ;
Nash, F. G. B. ;
Barigou, M. ;
Alexiadis, A. .
COMPUTERS IN BIOLOGY AND MEDICINE, 2017, 89 :96-103
[3]   Discrete multi-physics: A mesh-free model of blood flow in flexible biological valve including solid aggregate formation [J].
Ariane, Mostapha ;
Allouche, Mohamed Hatem ;
Bussone, Marco ;
Giacosa, Fausto ;
Bernard, Frederic ;
Barigou, Mostafa ;
Alexiadis, Alessio .
PLOS ONE, 2017, 12 (04)
[4]   Computational Fluid Dynamics Simulation on Blood Velocity and Vorticity of Venous Valve Behaviour [J].
Aziz, Nur Shazilah Bt ;
Ibrahim, Nabilah Bt ;
Abdullah, Kamil ;
Harun, Noor Hafizzatul Izzah Bt Mat .
9TH INTERNATIONAL CONFERENCE ON ROBOTIC, VISION, SIGNAL PROCESSING AND POWER APPLICATIONS: EMPOWERING RESEARCH AND INNOVATION, 2017, 398 :617-625
[5]  
Bower A.F., 2010, Applied mechanics of solids
[6]   Experimental studies of the effects of abnormal venous valves on fluid flow [J].
Buescher, CD ;
Nachiappan, B ;
Brumbaugh, JM ;
Hoo, KA ;
Janssen, HF .
BIOTECHNOLOGY PROGRESS, 2005, 21 (03) :938-945
[7]   Fluid-structure interaction simulations of venous valves: A monolithic ALE method for large structural displacements [J].
Calandrini, Sara ;
Aulisa, Eugenio .
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 2019, 35 (02)
[8]  
Chandran KB, 2007, BIOFLUID MECH HUMAN, DOI [10.1088/1751-8113/44/8/085201, DOI 10.1088/1751-8113/44/8/085201]
[9]   Biomechanical comparison between mono-, bi-, and tricuspid valve architectures [J].
Chen, Henry Y. ;
Berwick, Zachary ;
Krieger, Joshua ;
Chambers, Sean ;
Lurie, Fedor ;
Kassab, Ghassan S. .
JOURNAL OF VASCULAR SURGERY-VENOUS AND LYMPHATIC DISORDERS, 2014, 2 (02) :188-+
[10]  
Chen HY, 2010, COMPUTATIONAL CARDIOVASCULAR MECHANICS: MODELING AND APPLICATIONS IN HEART FAILURE, P141, DOI 10.1007/978-1-4419-0730-1_9