Opportunities for Photoacoustic-Guided Drug Delivery

被引：71

作者：

Xia, Jun ^{[1
]}

Kim, Chulhong ^{[2
]}

Lovell, Jonathan F. ^{[1
]}

机构：

[1] SUNY Buffalo, Dept Biomed Engn, Buffalo, NY 14260 USA

[2] Pohang Univ Sci & Technol POSTECH, Dept Creat IT Engn, Pohang, South Korea

来源：

CURRENT DRUG TARGETS | 2015年 / 16卷 / 06期

基金：

美国国家卫生研究院;

关键词：

Drug delivery; image-guided therapy; optoacoustic; photoacoustic; photothermal; theranostics; SENTINEL LYMPH-NODES; MULTISPECTRAL OPTOACOUSTIC TOMOGRAPHY; INFRARED PHOTOTHERMAL THERAPY; GOLD NANOPARTICLES; CARBON NANOTUBES; IN-VITRO; FUNCTIONAL CONNECTIVITY; THERMAL THERAPY; CONTRAST AGENTS; HIGH-RESOLUTION;

D O I：

10.2174/1389450116666150707100328

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Photoacoustic imaging (PAI) is rapidly becoming established as a viable imaging modality for small animal research, with promise of near-future human clinical translation. In this review, we discuss emerging prospects for photoacoustic-guided drug delivery. PAI presents opportunities for applications related to drug delivery, mainly with respect to either monitoring drug effects or monitoring drugs themselves. PAI is well-suited for imaging disease pathology and treatment response. Alternatively, PAI can be used to directly monitor the accumulation of various light-absorbing contrast agents or carriers with theranostic properties.

引用

页码：571 / 581

页数：11

共 123 条

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