p53-dependent induction of p21 and growth arrest: A critical role for PCAF-mediated histone acetylation

被引:17
作者
Eckner, Richard [1 ]
机构
[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Biochem & Mol Biol, Univ Hosp Canc Ctr, Newark, NJ 07103 USA
关键词
DNA-BINDING; P53; TRANSCRIPTION; ACTIVATION; APOPTOSIS; DOMAIN; DAMAGE; P300;
D O I
10.4161/cc.21235
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:2591 / 2592
页数:2
相关论文
共 9 条
[1]   Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain [J].
Gu, W ;
Roeder, RG .
CELL, 1997, 90 (04) :595-606
[2]   Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways [J].
Kasper, Lawryn H. ;
Thomas, Mary C. ;
Zambetti, Gerard P. ;
Brindle, Paul K. .
CELL CYCLE, 2011, 10 (02) :212-221
[3]   Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate [J].
Knights, Chad D. ;
Catania, Jason ;
Di Giovanni, Simone ;
Muratoglu, Selen ;
Perez, Ricardo ;
Swartzbeck, Amber ;
Quong, Andrew A. ;
Zhang, Xiaojing ;
Beerman, Terry ;
Pestell, Richard G. ;
Avantaggiati, Maria Laura .
JOURNAL OF CELL BIOLOGY, 2006, 173 (04) :533-544
[4]  
Liu L, 1999, MOL CELL BIOL, V19, P1202
[5]   The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3 [J].
Love, Ian M. ;
Sekaric, Pedja ;
Shi, Dingding ;
Grossman, Steven R. ;
Androphy, Elliot J. .
CELL CYCLE, 2012, 11 (13) :2458-2466
[6]   DNA damage activates p53 through a phosphorylation-acetylation cascade [J].
Sakaguchi, K ;
Herrera, JE ;
Saito, S ;
Miki, T ;
Bustin, M ;
Vassilev, A ;
Anderson, CW ;
Appella, E .
GENES & DEVELOPMENT, 1998, 12 (18) :2831-2841
[7]   Acetylation of the DNA Binding Domain Regulates Transcription-independent Apoptosis by p53 [J].
Sykes, Stephen M. ;
Stanek, Timothy J. ;
Frank, Amanda ;
Murphy, Maureen E. ;
McMahon, Steven B. .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (30) :20197-20205
[8]   Acetylation is indispensable for p53 activation [J].
Tang, Yi ;
Zhao, Wenhui ;
Chen, Yue ;
Zhao, Yingming ;
Gu, Wei .
CELL, 2008, 133 (04) :612-626
[9]   Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis [J].
Tang, Yi ;
Luo, Jianyuan ;
Zhang, Wenzhu ;
Gu, Wei .
MOLECULAR CELL, 2006, 24 (06) :827-839