Antibody Response after SARS-CoV-2 Infection with the Delta and Omicron Variant

被引：9

作者：

Blaszczuk, Agata ^{[1
]}

Michalski, Aleksander ^{[2
]}

Sikora, Dominika ^{[1
]}

Malm, Maria ^{[3
]}

Drop, Bartlomiej ^{[3
]}

Polz-Dacewicz, Malgorzata ^{[1
]}

机构：

[1] Med Univ Lublin, Dept Virol, SARS Lab, PL-20093 Lublin, Poland

[2] Outpatient Clin Lublin, Clin Mil Hosp 1, PL-20049 Lublin, Poland

[3] E Hlth Lab, Dept Comp Sci & Med Stat, PL-20090 Lublin, Poland

来源：

VACCINES | 2022年 / 10卷 / 10期

关键词：

SARS-CoV-2; COVID-19; SARS CoV-2 antibody; NCP; RBD; S2; delta variant; omicron variant; vaccination;

D O I：

10.3390/vaccines10101728

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The SARS-CoV-2 virus caused a worldwide COVID-19 pandemic. So far, 6,120,834 confirmed cases of COVID-19 with 116,773 deaths have been reported in Poland. According to WHO, a total of 54,662,485 vaccine doses have been administered. New variants emerge that become dominant. The aim of this study was a comparison of antibody level after infection caused by Delta and Omicron variants. The study included 203 persons who underwent mild COVID-19 despite two doses of vaccine. The obtained results indicate that a significantly lower titer was observed in patients with the Omicron variant infection. Therefore, these patients may be at risk of reinfection with new strains of the Omicron variant. Due to the possibility of reinfection, booster vaccinations are necessary. Further epidemiological and clinical studies are necessary to develop new prevention strategies.

引用

页数：8

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