One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using hydrochloric acid-β-cyclodextrin-combined catalysts

被引：7
|
作者：
Zhou, HX [1 ]
He, M [1 ]
Liu, CS [1 ]
Luo, GX [1 ]
机构：
[1] Liaoning Univ Petr & Chem Technol, Dept Chem, Liaoning, Peoples R China
来源：
LETTERS IN ORGANIC CHEMISTRY | 2006年 / 3卷 / 03期
关键词：
Biginelli reaction; dihydropyrimidinones; beta-cyclodextrin; one-pot; synthesis;
D O I：
10.2174/157017806775789985
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An improved approach has been found to carry out the Biginelli reaction for the synthesis of 3,4-dihydropyrimidin- 2(1H)-one derivatives. This synthesis was performed in the presence of hydrochloric acid and beta-cyclodextrin in ethanol solution. Compared with the classical Biginelli reaction conditions, this new approach has the advantage of excellent yields and short reaction time.
引用
收藏
页码：225 / 227
页数：3
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