One-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones using hydrochloric acid-β-cyclodextrin-combined catalysts

被引：8

作者：

Zhou, HX ^{[1
]}

He, M ^{[1
]}

Liu, CS ^{[1
]}

Luo, GX ^{[1
]}

机构：

[1] Liaoning Univ Petr & Chem Technol, Dept Chem, Liaoning, Peoples R China

来源：

LETTERS IN ORGANIC CHEMISTRY | 2006年 / 3卷 / 03期

关键词：

Biginelli reaction; dihydropyrimidinones; beta-cyclodextrin; one-pot; synthesis;

D O I：

10.2174/157017806775789985

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved approach has been found to carry out the Biginelli reaction for the synthesis of 3,4-dihydropyrimidin- 2(1H)-one derivatives. This synthesis was performed in the presence of hydrochloric acid and beta-cyclodextrin in ethanol solution. Compared with the classical Biginelli reaction conditions, this new approach has the advantage of excellent yields and short reaction time.

引用

页码：225 / 227

页数：3

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