Three new phenolic compounds from the leaves of Rosa sericea

被引：13

作者：

Li, Jin-Rong ^{[1
]}

Liu, Jie ^{[1
]}

He, Da-Hai ^{[1
]}

Xu, Hong-Xi ^{[2
]}

Ding, Li-Sheng ^{[1
]}

Bao, Wei-Kai ^{[1
]}

Zhou, Zhi-Qiong ^{[1
]}

Zhou, Yan ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Biol, Key Lab Mt Ecol Restorat & Bioresource Utilizat, Chengdu 610041, Peoples R China

[2] Shanghai Univ Tradit Chinese Med, Shanghai 201203, Peoples R China

来源：

FITOTERAPIA | 2013年 / 84卷

关键词：

Rosa sericea; Rosaceae; Flavonoid; Structure elucidation; Cytotoxicity; VITRO PHARMACOLOGICAL-ACTIVITY; FLAVONOL GLYCOSIDES; CONSTITUENTS; FRACTION; FRUITS; ACID; HIPS;

D O I：

10.1016/j.fitote.2012.12.019

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new flavonoids, quercetin-3-O-beta-D-xylopyranosyl-(1 -> 2)-alpha-D-ribopyranoside (1) and kaempferol-3-O-beta-D-xylopyranosyl-(1 -> 2)-alpha-D-ribopyranoside (2), and one new phenolic derivative, gallicin-p-O-(6'-O-caffeoyl)-beta-D-glucoside (3), together with twelve known compounds were isolated from the leaves of Rosa sericea (Rosaceae family). The structures of the new compounds were established by means of spectroscopic analysis including one- and two-dimensional NMR spectroscopy. Some of the isolated compounds were tested for the cytotoxicity of a breast cancer cell (MCF-7) line. The results showed that rubanthrone A (4) has moderate cytotoxicity against the MCF-7 cell line. (c) 2012 Elsevier B.V. All rights reserved.

引用

页码：332 / 337

页数：6

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