Exploring the Mechanism of Biomolecule Immobilization on Plasma-Treated Polymer Substrates Biomolecule Immobilization on Plasma-Treated Polymer

被引：0
|
作者：
Lock, E. H. [1 ]
North, S. H. [2 ]
Wojciechowski, J. [2 ]
Taitt, C. R. [2 ]
Walton, S. G. [1 ]
机构：
[1] USN, Res Lab, Div Plasma Phys, 4555 Overlook Ave SW, Washington, DC 20375 USA
[2] US Naval Acad, Res Lab, Ctr Bio Mol Sci & Engn, Washington, DC USA
来源：
TECHNOLOGICAL INNOVATIONS IN SENSING AND DETECTION OF CHEMICAL, BIOLOGICAL, RADIOLOGICAL, NUCLEAR THREATS AND ECOLOGICAL TERRORISM | 2012年
关键词：
BEAM-GENERATED PLASMAS; SURFACE;
D O I：
10.1007/978-94-007-2488-4_26
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
An electron beam-generated plasma source developed at NRL was used to modify polystyrene microtitre plates. A combination of complementary surface analytical and biochemical techniques was applied to evaluate the relationship between the biotic and abiotic layers, with particular emphasis on the efficiency of the preparation of polymer surfaces and its effectiveness for bioimmobilization. We conclude that the development of novel interface materials with superior transducing capabilities is dependent on the deeper understanding of the complex physicochemical, nanoscale interactions between the substrate surface and the biological components attached to it.
引用
收藏
页码：237 / 244
页数：8
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