West Nile virus and kidney disease

被引：0

作者：

Barzon, Luisa ^{[1
]}

Pacenti, Monia ^{[2
]}

Palu, Giorgio ^{[1
]}

机构：

[1] Univ Padua, Dept Mol Med, I-35121 Padua, Italy

[2] Padova Univ Hosp, Microbiol & Virol Dept, I-35128 Padua, Italy

来源：

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY | 2013年 / 11卷 / 05期

关键词：

chronic renal disease; flavivirus; kidney infection; nucleic acid testing; renal transplantation; urine; virus persistence; West Nile virus; UNITED-STATES; DENGUE VIRUS; TRANSPLANT RECIPIENTS; GOLDEN-HAMSTER; RISK-FACTORS; NEW-YORK; CLINICAL CHARACTERISTICS; MEDITERRANEAN BASIN; FLACCID PARALYSIS; IMMUNE-RESPONSES;

D O I：

10.1586/ERI.13.34

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

West Nile virus (WNV), the causative agent of West Nile fever and West Nile neuroinvasive disease in humans, has become endemic in many countries in all continents. Concerns on long-term mobility from WNV have arisen from recent studies that reported chronic kidney disease in patients who recovered from WNV infection, supported by data from animal models that showed prolonged excretion of the virus with urine. The purpose of this review is to summarize and discuss the results of studies in the literature that investigated WNV infection of the kidney in humans and in animal models and WNV excretion with urine, the potential damage to the kidney caused by WNV infection, the risk of WNV disease in kidney transplant recipients, the significance of detecting WNV in urine and its use in the diagnosis of WNV infection, and kidney involvement by other mosquito-borne flaviviruses.

引用

页码：479 / 487

页数：9

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