INCLUSION BODY HEPATITIS (IBH) OUTBREAK ASSOCIATED WITH FOWL ADENOVIRUS TYPE 8b IN BROILERS

被引:19
作者
Zadravec, M. [1 ]
Slavec, Brigita [1 ]
Krapez, U. [1 ]
Kajan, G. L. [2 ]
Racnik, J. [1 ]
Juntes, Polona [3 ]
Cizerl, Jursic Rahela [4 ]
Benko, Maria [2 ]
Rojs, Zorman Olga [1 ]
机构
[1] Vet Fac Ljubljana, Inst Poultry Hlth, Ljubljana 1000, Slovenia
[2] Hungarian Acad Sci, Vet Med Res Inst, H-1581 Budapest, Hungary
[3] Vet Fac Ljubljana, Inst Pathol Forens & Adm Vet Med, Ljubljana 1000, Slovenia
[4] Veterinarstvo Doo, Vet Practice Perutnina Ptuj, Ptuj, Slovenia
来源
ACTA VETERINARIA-BEOGRAD | 2013年 / 63卷 / 01期
关键词
broilers; FAdV8b; IBH outbreak; Slovenia; POLYMERASE-CHAIN-REACTION; CHICKEN ANEMIA VIRUS; BURSAL DISEASE VIRUS; AVIAN ADENOVIRUSES; LYMPHOID ORGANS; HYBRIDIZATION; PCR;
D O I
10.2298/AVB1301101Z
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The causative agent of inclusion body hepatitis (IBH) was identified as fowl adenovirus (FAdV) type 8b, a member of the Fowl adenovirus E species, based on PCR results of adenoviral polymerase and the hexon gene in an outbreak of acute mortality that affected a broiler flock of 12,000 animals. In two waves of elevated mortality rate, a total of 264 chickens were found dead. Affected birds showed ruffled feathers, depression, watery droppings and limping. The most common pathological lesions seen on necropsy were pale, swollen and friable livers. On histological examination, acute hepatitis characterized by necrosis of hepatocytes, with large basophilic intranuclear inclusion bodies, were observed. In addition, infectious bursal disease virus and infectious bronchitis virus were detected in the same flock.
引用
收藏
页码:101 / 110
页数:10
相关论文
共 32 条
[21]   Genotyping of Canadian isolates of fowl adenoviruses [J].
Ojkic, Davor ;
Martin, Emily ;
Swinton, Janet ;
Vaillancourt, Jean-Pierre ;
Boulianne, Martine ;
Gomis, Susantha .
AVIAN PATHOLOGY, 2008, 37 (01) :95-100
[22]  
Rojs Zorman, 2011, ACTA VET HU IN PRESS
[23]   ROLE OF INFECTIOUS BURSAL AGENT AND SEVERAL AVIAN ADENOVIRUSES IN HEMORRHAGIC-APLASTIC-ANEMIA SYNDROME AND GANGRENOUS DERMATITIS [J].
ROSENBERGER, JK ;
KLOPP, S ;
ECKROADE, RJ ;
KRAUSS, WC .
AVIAN DISEASES, 1975, 19 (04) :717-729
[24]   CHARACTERIZATION OF AVIAN ADENOVIRUSES ASSOCIATED WITH INCLUSION BODY HEPATITIS [J].
SAIFUDDIN, M ;
WILKS, CR ;
MURRAY, A .
NEW ZEALAND VETERINARY JOURNAL, 1992, 40 (02) :52-55
[25]   Fowl adenovirus (FAdV) serotype 4 causes depletion of B and T cells in lymphoid organs in specific pathogen-free chickens following experimental infection [J].
Schonewille, Esther ;
Singh, Amarjit ;
Goebel, Thomas W. ;
Gerner, Wilhelm ;
Saalmueller, Armin ;
Hess, Michael .
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 2008, 121 (1-2) :130-139
[26]   Immunosuppression in broiler chicks fed aflatoxin and inoculated with fowl adenovirus serotype-4 (FAV-4) associated with hydropericardium syndrome [J].
Shivachandra, SB ;
Sah, RL ;
Singh, SD ;
Kataria, JM ;
Manimaran, K .
VETERINARY RESEARCH COMMUNICATIONS, 2003, 27 (01) :39-51
[27]   MEGA4: Molecular evolutionary genetics analysis (MEGA) software version 4.0 [J].
Tamura, Koichiro ;
Dudley, Joel ;
Nei, Masatoshi ;
Kumar, Sudhir .
MOLECULAR BIOLOGY AND EVOLUTION, 2007, 24 (08) :1596-1599
[28]   CLUSTAL-W - IMPROVING THE SENSITIVITY OF PROGRESSIVE MULTIPLE SEQUENCE ALIGNMENT THROUGH SEQUENCE WEIGHTING, POSITION-SPECIFIC GAP PENALTIES AND WEIGHT MATRIX CHOICE [J].
THOMPSON, JD ;
HIGGINS, DG ;
GIBSON, TJ .
NUCLEIC ACIDS RESEARCH, 1994, 22 (22) :4673-4680
[29]   Chicken anemia virus and fowl adenoviruses: Association to induce the inclusion body hepatitis hydropericardium syndrome [J].
Toro, H ;
Gonzalez, C ;
Cerda, L ;
Hess, M ;
Reyes, E ;
Geisse, C .
AVIAN DISEASES, 2000, 44 (01) :51-58
[30]  
Toro H, 2002, AVIAN DIS, V46, P547, DOI 10.1637/0005-2086(2002)046[0547:POIBHH]2.0.CO