Efficient Synthesis of Conjugated 1,3,4-Thiadiazole Hybrids through Palladium-Catalyzed Cross-Coupling of 2,5-Bis(4-bromophenyl)-1,3,4-thiadiazole with Boronic Acids

被引：10

作者：

Wroblowska, Monika ^{[1
]}

Kudelko, Agnieszka ^{[1
]}

Lapkowski, Mieczyslaw ^{[2
,3
]}

机构：

[1] Silesian Tech Univ, Dept Chem Organ Technol & Petrochem, PL-44100 Gliwice, Poland

[2] Silesian Tech Univ, Dept Phys Chem & Technol Polymers, PL-44100 Gliwice, Poland

[3] Polish Acad Sci, Ctr Polymer & Carbon Mat, PL-41819 Zabrze, Poland

来源：

SYNLETT | 2015年 / 26卷 / 15期

关键词：

heterocycles; cross-coupling; phase-transfer catalysis; palladium; catalysis; LIGHT-EMITTING-DIODES; ANTIMICROBIAL ACTIVITY; SIDE-CHAIN; DEVICE; ELECTROLUMINESCENCE; 1,3,4-OXADIAZOLES; ELECTROCHEMISTRY; DERIVATIVES; POLYMER;

D O I：

10.1055/s-0034-1378826

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New derivatives of 2,5-bis(4-heteroarylphenyl)-1,3,4-thiadiazole were synthesized under Suzuki cross-coupling reactions from 2,5-bis(4-bromophenyl)-1,3,4-thiadiazole and commercially available boronic acids. Reactions were conducted in a two-phase solvent system in the presence of catalytic amounts of tetrakis(triphenylphosphine)palladium(0), cesium carbonate as a base, and tetrabutylammonium bromide playing a role of a phase-transfer catalyst.

引用

页码：2127 / 2130

页数：4

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