A ratiometric fluorescent probe based on a BODIPY-DCDHF conjugate for the detection of hypochlorous acid in living cells

被引：112

作者：

Park, Jeesook ^{[1
]}

Kim, Hyunjin ^{[2
]}

Choi, Yongdoo ^{[2
]}

Kim, Youngmi ^{[1
]}

机构：

[1] Dankook Univ, Inst Nanosensor & Biotechnol, Dept Chem, Yongin 448701, Gyeonggi Do, South Korea

[2] Natl Canc Ctr, Mol Imaging & Therapy Branch, Goyang Si 410769, Gyeonggi Do, South Korea

来源：

ANALYST | 2013年 / 138卷 / 12期

关键词：

HUMAN ATHEROSCLEROTIC LESIONS; MYELOPEROXIDASE; INFLAMMATION; MACROPHAGES; OXIDATION; CATALYST; STRESS;

D O I：

10.1039/c3an36820c

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A colorimetric and ratiometric fluorescent probe consisting of a boron-dipyrromethene (BODIPY) dye conjugated with a 2-dicyanomethylene-3-cyano-2,5-dihydrofuran (DCDHF) group has been designed for the selective and sensitive detection of HOCl/OCl- via oxidative cleavage of an alkene linker between BODIPY and DCDHF.

引用

页码：3368 / 3371

页数：4

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