Predictors of Time to Effective and Optimal Antimicrobial Therapy in Patients With Positive Blood Cultures Identified via Molecular Rapid Diagnostic Testing

被引：5
作者：
Beganovic, Maya [1 ]
Timbrook, Tristan T. [2 ,3 ]
Wieczorkiewicz, Sarah M. [1 ]
机构：
[1] Advocate Lutheran Gen Hosp, Dept Pharm, 1775 Dempster St, Park Ridge, IL 60068 USA
[2] Univ Utah Hlth, Dept Pharm, Salt Lake City, UT USA
[3] Salt Lake City Vet Affairs Med Ctr, Salt Lake City, UT USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2019年 / 6卷 / 01期
关键词：
antimicrobial stewardship; bloodstream infections; metrics; predictors; rapid diagnostic testing; DESORPTION IONIZATION-TIME; STEWARDSHIP TEAM; CLINICAL IMPACT; INTERVENTION; OUTCOMES;
D O I：
10.1093/ofid/ofy350
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Antimicrobial stewardship (AMS) programs integrated with rapid diagnostic tests optimize patient outcomes and reduce time to effective therapy (TTET) and time to optimal therapy (TTOT). This study identifies predictors of TTET and TTOT among patients with positive blood cultures and identifies limitations to current TTOT definitions and outcomes.
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