The Genomic Blueprint of Salmonella enterica subspecies enterica serovar Typhi P-stx-12

被引：4

作者：

Ong, Su Yean ^{[1
]}

Pratap, Chandra Bhan ^{[2
]}

Wan, Xuehua ^{[3
]}

Hou, Shaobin ^{[3
]}

Rahman, Ahmad Yamin Abdul ^{[1
]}

Saito, Jennifer A. ^{[1
]}

Nath, Gopal ^{[2
]}

Alam, Maqsudul ^{[3
]}

机构：

[1] Univ Sains Malaysia, Ctr Chem Biol, George Town, Malaysia

[2] Banaras Hindu Univ, Inst Med Sci, Dept Microbiol, Varanasi 221005, Uttar Pradesh, India

[3] Univ Hawaii, Honolulu, HI USA

来源：

STANDARDS IN GENOMIC SCIENCES | 2013年 / 7卷 / 03期

关键词：

Enterobacteriaceae; Salmonella; Typhi; Gram-negative; host-specific; pathogen; Typhoid Fever; ANNOTATION; BACTERIA; SEQUENCE; IDENTIFICATION; VISUALIZATION; ALIGNMENT; SYSTEM; GENES; FEVER; TOOL;

D O I：

10.4056/sigs.3286690

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Salmonella enterica subspecies enterica serovar Typhi is a rod-shaped, Gram-negative, facultatively anaerobic bacterium. It belongs to the family Enterobacteriaceae in the class Gammaproteobacteria, and has the capability of residing in the human gallbladder by forming a biofilm and hence causing the person to become a typhoid carrier. Here we present the complete genome of Salmonella enterica subspecies enterica serotype Typhi strain P-stx-12, which was isolated from a chronic carrier in Varanasi, India. The complete genome comprises a 4,768,352 bp chromosome with a total of 98 RNA genes, 4,691 protein-coding genes and a 181,431 bp plasmid. Genome analysis revealed that the organism is closely related to Salmonella enterica serovar Typhi strain Ty2 and Salmonella enterica serovar Typhi strain CT18, although their genome structure is slightly different.

引用

页码：483 / 496

页数：14

共 48 条

[1] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[2] BASIC LOCAL ALIGNMENT SEARCH TOOL [J].

ALTSCHUL, SF ;

GISH, W ;

MILLER, W ;

MYERS, EW ;

LIPMAN, DJ .

JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) :403-410

[3] Automated system for gene annotation and metabolic pathway reconstruction using general sequence databases [J].

Alves, Joao M. P. ;

Buck, Gregory A. .

CHEMISTRY & BIODIVERSITY, 2007, 4 (11) :2593-2602

[4]

[Anonymous], 1958, INT B BACT NOMENCL T, V8, P73

[5]

[Anonymous], 2012, Molecular Cloning: A Laboratory Manual

[6]

[Anonymous], 2005, Int J Syst Evol Microbiol, V55, P2235

[7] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[8] The genome of Salmonella enterica serovar typhi [J].

Baker, Stephen ;

Dougan, Gordon .

CLINICAL INFECTIOUS DISEASES, 2007, 45 :S29-S33

[9] Weighted neighbor joining: A likelihood-based approach to distance-based phylogeny reconstruction [J].

Bruno, WJ ;

Socci, ND ;

Halpern, AL .

MOLECULAR BIOLOGY AND EVOLUTION, 2000, 17 (01) :189-197

[10] Detection of and discrimination between gram-positive and gram-negative bacteria in intraocular samples by using nested PCR [J].

Carroll, NM ;

Jaeger, EEM ;

Choudhury, S ;

Dunlop, AAS ;

Matheson, MM ;

Adamson, P ;

Okhravi, N ;

Lightman, S .

JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (05) :1753-1757

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