DEMENTIA A new algorithm for molecular diagnostics in FTLD

被引：32

作者：

Borroni, Barbara ^{[1
]}

Padovani, Alessandro ^{[1
]}

机构：

[1] Univ Brescia, Ctr Neurodegenerat Disorders, I-25100 Brescia, Italy

来源：

NATURE REVIEWS NEUROLOGY | 2013年 / 9卷 / 05期

关键词：

FRONTOTEMPORAL DEMENTIA; C9ORF72; PROGRANULIN; SIGNATURES; TAU;

D O I：

10.1038/nrneurol.2013.72

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Genetic diagnosis of frontotemporal lobar degeneration has become challenging since the identification of a number of autosomal dominantly inherited causative mutations. As highlighted in a new paper, careful characterization of the clinical picture associated with a specific gene defect is mandatory to guide genetic screening, and to establish a diagnostic algorithm for neurology practice.

引用

页码：241 / 242

页数：2

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