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A Radiologist's Guide to Treatment Response Criteria in Oncologic Imaging: Anatomic Imaging Biomarkers
被引:12
作者:
Rezai, Pedram
[1
]
Pisaneschi, Mark J.
[1
]
Feng, Chun
[1
]
Yaghmai, Vahid
[2
]
机构:
[1] John H Stroger Jr Hosp, Dept Radiol, Chicago, IL 60612 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Radiol, Chicago, IL 60611 USA
关键词:
anatomic imaging biomarker;
imaging biomarker;
RECIST;
volumetric evaluation;
WHO guideline;
TUMOR RESPONSE;
SOLID TUMORS;
HEPATOCELLULAR-CARCINOMA;
NEOADJUVANT CHEMOTHERAPY;
DRUG-DEVELOPMENT;
CLINICAL-TRIALS;
VOLUMETRIC MEASUREMENTS;
PULMONARY METASTASES;
COMPUTED-TOMOGRAPHY;
IMATINIB MESYLATE;
D O I:
10.2214/AJR.12.9862
中图分类号:
R8 [特种医学];
R445 [影像诊断学];
学科分类号:
1002 ;
100207 ;
1009 ;
摘要:
OBJECTIVE. The purpose of this article is to describe the imaging biomarkers of treatment response and provide an overview of anatomic imaging biomarkers. CONCLUSION. Imaging biomarkers of treatment response have evolved into the primary endpoint of response in most phase 2 studies. Anatomic imaging biomarkers are applied to depict change in tumor size in response to treatment and are currently the most commonly applied method of treatment response evaluation.
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页码:237 / 245
页数:9
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