A chromatic explosion: the development and future of multiparameter flow cytometry

被引：121

作者：

Chattopadhyay, Pratip K. ^{[1
]}

Hogerkorp, Carl-Magnus ^{[1
]}

Roederer, Mario ^{[1
]}

机构：

[1] NIAID, ImmunoTechnol Sect, Immunol Lab, Vaccine Res Ctr,NIH, Bethesda, MD 20892 USA

来源：

IMMUNOLOGY | 2008年 / 125卷 / 04期

关键词：

flow cytometry; T cells; tetramers; fluorochromes; data analysis;

D O I：

10.1111/j.1365-2567.2008.02989.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.

引用

页码：441 / 449

页数：9

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