Cardiovascular CT angiography in neonates and children: Image quality and potential for radiation dose reduction with iterative image reconstruction techniques

被引：50

作者：

Tricarico, Francesco ^{[1
,2
]}

Hlavacek, Anthony M. ^{[1
,3
]}

Schoepf, U. Joseph ^{[1
,3
,4
]}

Ebersberger, Ullrich ^{[1
,5
]}

Nance, John W., Jr. ^{[1
,6
]}

Vliegenthart, Rozemarijn ^{[1
,7
]}

Cho, Young Jun ^{[1
,8
]}

Spears, J. Reid ^{[1
]}

Secchi, Francesco ^{[1
,9
]}

Savino, Giancarlo ^{[2
]}

Marano, Riccardo ^{[2
]}

Schoenberg, Stefan O. ^{[10
]}

Bonomo, Lorenzo ^{[2
]}

Apfaltrer, Paul ^{[1
,10
]}

机构：

[1] Med Univ S Carolina, Dept Radiol & Radiol Sci, Charleston, SC 29401 USA

[2] Univ Cattolica Sacro Cuore, Dept Bioimaging & Radiol Sci, A Gemelli Hosp, I-00168 Rome, Italy

[3] Med Univ S Carolina, Childrens Hosp, Div Pediat Cardiol, Charleston, SC 29401 USA

[4] Med Univ S Carolina, Dept Med, Div Cardiol, Charleston, SC 29401 USA

[5] Heart Ctr Munich Bogenhausen, Dept Cardiol & Intens Care Med, Munich, Germany

[6] Johns Hopkins Univ Hosp, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA

[7] Univ Groningen, Univ Med Ctr Groningen, Dept Radiol, Ctr Med Imaging North East Netherlands, Groningen, Netherlands

[8] Konyang Univ, Dept Radiol, Sch Med, Taejon, South Korea

[9] Univ Milan, Sch Med, IRCCS Policlin San Donato, Dept Med & Surg Sci,Radiol Unit, Milan, Italy

[10] Heidelberg Univ, Med Fac Mannheim, Univ Med Ctr Mannheim, Inst Clin Radiol & Nucl Med, Mannheim, Germany

来源：

EUROPEAN RADIOLOGY | 2013年 / 23卷 / 05期

关键词：

Computed tomography; Congenital heart disease; Radiation dose; Iterative image reconstruction; Pediatric imaging; CONGENITAL HEART-DISEASE; TUBE CURRENT MODULATION; COMPUTED-TOMOGRAPHY; PEDIATRIC CT; CANCER RISKS; EXPOSURE; INFANTS; ADULTS; CHEST; AGE;

D O I：

10.1007/s00330-012-2734-5

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

To evaluate image quality (IQ) of low-radiation-dose paediatric cardiovascular CT angiography (CTA), comparing iterative reconstruction in image space (IRIS) and sinogram-affirmed iterative reconstruction (SAFIRE) with filtered back-projection (FBP) and estimate the potential for further dose reductions. Forty neonates and children underwent low radiation CTA with or without ECG synchronisation. Data were reconstructed with FBP, IRIS and SAFIRE. For ECG-synchronised studies, half-dose image acquisitions were simulated. Signal noise was measured and IQ graded. Effective dose (ED) was estimated. Mean absolute and relative image noise with IRIS and full-dose SAFIRE was lower than with FBP (P < 0.001), while SNR and CNR were higher (P < 0.001). Image noise was also lower and SNR and CNR higher in half-dose SAFIRE studies compared with full-and half-dose FBP studies (P < 0.001). IQ scores were higher for IRIS, full-dose SAFIRE and half-dose SAFIRE than for full-dose FBP and higher for half-dose SAFIRE than for half-dose FBP (P < 0.05). Median weight-specific ED was 0.3 mSv without and 1.36 mSv with ECG synchronisation. The estimated ED of half-dose SAFIRE studies was 0.68 mSv. IR improves image noise, SNR, CNR and subjective IQ compared with FBP in low-radiation-dose paediatric CTA and allows further dose reductions without compromising diagnostic IQ. aEuro cent Iterative reconstruction techniques significantly improve non-invasive cardiovascular CT in children. aEuro cent Using half traditional radiation dose image quality is higher with iterative reconstruction. aEuro cent Iterative reconstruction techniques may allow further radiation reductions in paediatric cardiovascular CT.

引用

页码：1306 / 1315

页数：10

共 38 条

[1] Introduction to cardiac imaging in infants and children: Techniques, potential, and role in the imaging work-up of various cardiac malformations and other pediatric heart conditions [J].