Radiometals for Combined Imaging and Therapy

被引：320

作者：

Cutler, Cathy S. ^{[1
]}

Hennkens, Heather M. ^{[1
]}

Sisay, Nebiat ^{[1
,2
]}

Huclier-Markai, Sandrine ^{[3
]}

Jurisson, Silvia S. ^{[2
]}

机构：

[1] Univ Missouri, Res Reactor Ctr, Columbia, MO 65211 USA

[2] Univ Missouri, Dept Chem, Columbia, MO 65211 USA

[3] Univ Nantes, Lab Subatech, UMR 6457, Ecole Mines Nantes,CNRS IN2P3, F-44307 Nantes 3, France

来源：

CHEMICAL REVIEWS | 2013年 / 113卷 / 02期

关键词：

POSITRON EMISSION TOMOGRAPHY; METASTATIC BONE PAIN; COPPER-64-LABELED MONOCLONAL-ANTIBODY; PARTICLE-EMITTING RADIONUCLIDES; CLUSTER-LABELED ANTIBODIES; NUCLEAR-MEDICINE THERAPY; RAY CRYSTAL-STRUCTURES; DOTA-BINDING ANTIBODY; SCHIFF-BASE COMPLEXES; IN-VIVO EVALUATION;

D O I：

10.1021/cr3003104

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A study was conducted to demonstrate the use of radiometals for combined imaging and therapy. The study presented radiometals that had the nuclear properties required for use in theranostic applications for imaging and therapy. Their chemistry and production methods were discussed, along with examples of preclinical and clinical uses. A number of radiometals had been evaluated for positron emission tomography (PET) due to their favorable nuclear properties. The choice of type and energy of the particle emission was determined by the size of the lesion or tumor being treated, site of delivery, whether the tumor was homogeneous, and whether the dose was delivered uniformly to each cell. A major advantage of using such nanosized radioactive particles was their potential to contain numerous radioactive atoms within a single nanoparticle.

引用

页码：858 / 883

页数：26

共 213 条

[61] SYNTHESIS AND CHARACTERIZATION OF NEUTRAL M(V)O (M = TC, RE) AMINE-THIOL COMPLEXES CONTAINING A PENDANT PHENYLPIPERIDINE GROUP [J].

FRANCESCONI, LC ;

GRACZYK, G ;

WEHRLI, S ;

SHAIKH, SN ;

MCCLINTON, D ;

LIU, S ;

ZUBIETA, J ;

KUNG, HF .

INORGANIC CHEMISTRY, 1993, 32 (14) :3114-3124

[62] Comparative studies of Cu-64-ATSM and C-11-acetate in an acute myocardial infarction model:: Ex vivo imaging of hypoxia in rats [J].

Fujibayashi, Y ;

Cutler, CS ;

Anderson, CJ ;

McCarthy, DW ;

Jones, LA ;

Sharp, T ;

Yonekura, Y ;

Welch, MJ .

NUCLEAR MEDICINE AND BIOLOGY, 1999, 26 (01) :117-121

[63] Design and characterization of α-melanotropin peptide analogs cyclized through rhenium and technetium metal coordination [J].

Giblin, MF ;

Wang, N ;

Hoffman, TJ ;

Jurisson, SS ;

Quinn, TP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (22) :12814-12818

[64] COMPLEXES OF RHODIUM(3) WITH CHLORINE + PYRIDINE [J].

GILLARD, RD ;

WILKINSON, G .

JOURNAL OF THE CHEMICAL SOCIETY, 1964, (APR) :1224-&

[65] CHEMICAL EFFECTS OF NUCLEAR TRANSFORMATIONS OF COMPLEXED METAL ATOMS .I. BETA-DECAY OF 144CE AND 143CE COMPLEXED WITH POLYAMINOPOLYCARBOXYLIC ACID CHELATING LIGANDS [J].

GLENTWORTH, P ;

WRIGHT, CL .

JOURNAL OF INORGANIC & NUCLEAR CHEMISTRY, 1969, 31 (05) :1263-+

[66] A new macrocyclic N3S2 ligand and its nickel(II), cobalt(II), rhodium(III)-103, and rhodium(III)-105 complexes [J].

Goodman, DC ;

Reibenspies, JH ;

Goswami, N ;

Jurisson, S ;

Darensbourg, MY .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (21) :4955-4963

[67] Rhodium-105 tetrathioether complexes: Radiochemistry and initial biological evaluation [J].

Goswami, N ;

Higginbotham, C ;

Volkert, W ;

Alberto, R ;

Nef, W ;

Jurisson, S .

NUCLEAR MEDICINE AND BIOLOGY, 1999, 26 (08) :951-957

[68] Rhodium(III) complexes with acyclic tetrathioether ligands. Effects of backbone chain length on the conformation of the Rh(III) complex [J].

Goswami, N ;

Alberto, R ;

Barnes, CL ;

Jurisson, S .

INORGANIC CHEMISTRY, 1996, 35 (26) :7546-7555

[69] RH-105 AS A POTENTIAL RADIOTHERAPEUTIC AGENT [J].

GRAZMAN, B ;

TROUTNER, DE .

APPLIED RADIATION AND ISOTOPES, 1988, 39 (03) :257-260

[70]

GREEN MA, 1988, J NUCL MED, V29, P1549

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