Baicalein - main active flavonoid from Scutellaria baicalensis - voltammetric sensing in human samples using boron doped diamond electrode

被引：34

作者：

Kuzmanovic, Darko ^{[1
]}

Stankovic, Dalibor M. ^{[2
]}

Manojlovic, Dragan ^{[1
]}

Kalcher, Kurt ^{[3
]}

Roglic, Goran ^{[1
]}

机构：

[1] Univ Belgrade, Fac Chem, Belgrade 11000, Serbia

[2] Univ Belgrade, Fac Chem, Innovat Ctr, Belgrade 11000, Serbia

[3] Karl Franzens Univ Graz, Inst Chem Analyt Chem, A-8010 Graz, Austria

来源：

关键词：

Baicalein; Boron doped diamond electrode; Square wave voltammetry; PERFORMANCE LIQUID-CHROMATOGRAPHY; CANCER CELL-LINES; MAJOR FLAVONOIDS; RADIX; WOGONIN; GEORGI; QUANTIFICATION; GLUCURONIDES; ANTIOXIDANT; WOGONOSIDE;

D O I：

10.1016/j.diamond.2015.06.002

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In this study we proposed electrochemical behavior and determination of baicalein, main active flavonoid from Scutellaria baicalensis, using boron doped diamond electrode. In Britton-Robinson buffer solution, pH 2, baicalein provides two single oval shape oxidation peaks at +0.5 V/Ag-AgCl and a second one at +0.8 V/Ag-AgCl. For quantification of baicalein square wave voltammetry was used. Under optimized parameters calibration curve was linear over the range 1-95 mu M with detection limit of 0.26 mu M. After eight successful measurements repeatability was 3.7%. Proposed method was applied for determination of baicalein in real samples with excellent recovery. The influence of the most common interferences, biomolecules presented in urine was investigated. The developed approach could be beneficial in analysis of widely used flavonoid in biological samples. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：35 / 39

页数：5

共 28 条

[1]

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