Varicella-Like Cutaneous Toxoplasmosis in a Patient with Aplastic Anemia

被引:5
作者
Zimmermann, Stefan [1 ]
Hadaschik, Eva [2 ,3 ]
Dalpke, Alexander [1 ]
Hassel, Jessica C. [2 ,3 ]
Ajzenberg, Daniel [4 ]
Tenner-Racz, Klara [5 ]
Lehners, Nicola [6 ]
Kapaun, Annette [1 ]
Schnitzler, Paul [1 ]
机构
[1] Heidelberg Univ, Dept Infect Dis, Heidelberg, Germany
[2] Heidelberg Univ, Dept Dermatol, Heidelberg, Germany
[3] Univ Limoges, Ctr Hosp Univ Dupuytren, Ctr Natl Reference Toxoplasmose, Toxoplasma Biol Resource Ctr, Limoges, France
[4] Univ Limoges, INSERM, UMR 1094, Lab Parasitol Mycol,Fac Med, Limoges, France
[5] Bernhard Nocht Inst Trop Med, Hamburg, Germany
[6] Heidelberg Univ, Dept Internal Med, Heidelberg, Germany
关键词
TIME PCR ASSAY; GONDII; AF146527; TRANSPLANTATION; PNEUMONIA; INFECTION; DIAGNOSIS;
D O I
10.1128/JCM.02851-12
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A 60-year-old patient with aplastic anemia presented with vesicular varicella-like skin lesions on her face, arms, legs, back, and abdomen. However, diagnosis for herpetic infection was negative. Findings of a skin biopsy led to a tentative histologic diagnosis of toxoplasmosis, and infection with Toxoplasma gondii was confirmed by immunohistochemistry and PCR. Cutaneous toxoplasmosis is a rare finding in immunocompromised patients and might mimic other infectious diseases, and vesicular lesions associated with toxoplasmosis have not been reported previously.
引用
收藏
页码:1341 / 1344
页数:4
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