Interferon Gamma Inhibits Th2 Induced Mucus Metaplasia in vivo Through Effects on Epithelial IL-4 and IL-13 Receptor Expression, and Inhibition of Stat6 Phosphorylation

被引：0
|
作者：
Provost, K.
Niu, N.
Homer, R. J.
Cohn, L. E.
机构：
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2010年 / 181卷
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A4038
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Expression of IL-2γ receptor subunit by human keratinocytes in epidermis is induced through STAT6 and STAT3 activation by IL-4 and IL-13
    Progneaux, A.
    Dotreppe, C.
    de Rouvroit, C. Lambert
    Poumay, Y.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023, 143 (05) : S124 - S124
  • [2] Interferon-[gamma] suppresses STAT6 phosphorylation in Th1 cells by inhibiting the recruitment of STAT6 to the IL-4 receptor
    Huang, H
    Huang, Z
    Xin, JP
    Coleman, J
    FASEB JOURNAL, 2004, 18 (04): : A57 - A57
  • [3] Regulation of IL-4 and IL-13 expression in TH2 cells
    Guo, LY
    Hu-Li, J
    Paul, W
    FASEB JOURNAL, 2005, 19 (04): : A902 - A902
  • [4] IL-4 and IL-13 Promote Proliferation of Mammary Epithelial Cells through STAT6 and IRS-1
    Wu, Wan-Ju
    Wang, Sue-Hong
    Wu, Chun-Chi
    Su, Yi-An
    Chiang, Chin-Yin
    Lai, Ching-Hong
    Wang, Tsung-Hsiang
    Cheng, Tsung-Lin
    Kuo, Jia-Yu
    Hsu, Tsai-Ching
    Lin, Ting-Hui
    Lee, Yi-Ju
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
  • [5] The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development
    Khaled, Walid T.
    Read, Eliot K. C.
    Nicholson, Sandra E.
    Baxter, Fiona O.
    Brennan, Amelia J.
    Came, Paul J.
    Sprigg, Naomi
    McKenzie, Andrew N. J.
    Watson, Christine J.
    DEVELOPMENT, 2007, 134 (15): : 2739 - 2750
  • [6] Th2 Cytokines IL-4 and IL-13 Downregulate Paxillin Expression in Bronchial Airway Epithelial Cells
    Gail Ramirez-Icaza
    Kamal A. Mohammed
    Najmunnisa Nasreen
    Robert D. Van Horn
    Joyce A. Hardwick
    Kerry L. Sanders
    Jun Tian
    Carlos Ramirez-Icaza
    Mary T. Johnson
    Veena B. Antony
    Journal of Clinical Immunology, 2004, 24 : 426 - 434
  • [7] Th2 cytokines IL-4 and IL-13 downregulate paxillin expression in bronchial airway epithelial cells
    Ramirez-Icaza, G
    Mohammed, KA
    Nasreen, N
    Van Horn, RD
    Hardwick, JA
    Sanders, KL
    Tian, J
    Ramirez-Icaza, C
    Johnson, MT
    Antony, VB
    JOURNAL OF CLINICAL IMMUNOLOGY, 2004, 24 (04) : 426 - 434
  • [8] A murine Il-4 antagonist mutant protein inhibits Il-4-and Il-13-induced STAT6 phosphorylation and IgE production
    Tomkinson, A
    Pratt, JC
    Duez, C
    Joetham, A
    Gundel, R
    Gelfand, EW
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (02) : S61 - S61
  • [9] EFFECTS OF TH2 CYTOKINES IL-4 AND IL-13 ON LYMPHATIC VESSELS IN THE LUNG
    Sin, K. H.
    Rpkataru
    Lee, S. H.
    RESPIROLOGY, 2013, 18 : 20 - 20
  • [10] Corticosteroid inhibits IL-4 signaling through down-regulation of IL-4 receptor and STAT6 activity
    So, EY
    Kim, SH
    Park, HH
    Cho, BS
    Lee, CE
    FEBS LETTERS, 2002, 518 (1-3) : 53 - 59
12345