A Linear Permanent Magnet Synchronous Motor for Large Volume Needle-Free Jet Injection

被引:14
作者
Do, Nick N. L. [1 ]
Taberner, Andrew James [1 ,2 ]
Ruddy, Bryan P. [1 ,2 ]
机构
[1] Univ Auckland, Auckland Bioengn Inst, Auckland 1010, New Zealand
[2] Univ Auckland, Dept Engn Sci, Auckland 1010, New Zealand
关键词
Actuators; design optimization; drug delivery; electromechanical systems; linear permanent magnet synchronous motor (LPMSM); magnetic fields; FIELD; OPTIMIZATION; DESIGN; SKIN;
D O I
10.1109/TIA.2018.2880417
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Needle-free jet injection allows delivery of liquid drugs through the skin in the form of a narrow fluid jet traveling at high speed, minimizing the risk of accidents. The use of a controllable actuator to drive this process has many advantages, but the voice coil actuators previously used are too large and heavy for practical use with common injection volumes (1 mL). We instead propose a compact slotless tubular linear permanent magnet synchronous motor design for jet injection. The design was determined by utilizing a semi-analytical electromagnetic modeling technique to predict the performance of any given motor design, an optimization scheme for the motor mass at a given power dissipation, and an automated routine for estimating cogging force using finite-element analysis. A prototype motor was constructed, with a nominal mass of 322 g, a stroke of 80 mm, and a target operating power of 1.2 kW; experimental data show that the motor constant is within 10% of the target, and that the cogging force is in close agreement with the model. Test ejection of water into a force sensor verified that the motor is fit for needle-free injection. The design methodology explained here shows the benefits to integrated design optimization of both the actuator and the load, particularly in systems that drive fluid pressure loads, and also opens the door to controllable injector designs for larger volumes.
引用
收藏
页码:1437 / 1446
页数:10
相关论文
共 20 条
[1]   Analysis of magnetic field distribution of a cylindrical discrete Halbach permanent magnet linear generator [J].
Arof, Wijono H. ;
Ping, H. W. .
IET ELECTRIC POWER APPLICATIONS, 2010, 4 (08) :629-636
[2]   Analytical field computation of a tubular permanent-magnet linear motor [J].
Bianchi, N .
IEEE TRANSACTIONS ON MAGNETICS, 2000, 36 (05) :3798-3801
[3]  
Do NNL, 2017, IEEE ENER CONV, P4734, DOI 10.1109/ECCE.2017.8096806
[4]   Development and Performance of a Controllable Autoloading Needle-Free Jet Injector [J].
Hemond, Brian D. ;
Taberner, Andrew ;
Hogan, Cathy ;
Crane, Bryan ;
Hunter, Ian W. .
JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME, 2011, 5 (01)
[5]   Needle-free delivery of macromolecules through the skin using controllable jet injectors [J].
Hogan, Nora C. ;
Taberner, Andrew J. ;
Jones, Lynette A. ;
Hunter, Ian W. .
EXPERT OPINION ON DRUG DELIVERY, 2015, 12 (10) :1637-1648
[6]  
Jin J.-M., 2014, FINITE ELEMENT METHO
[7]   Power-efficient controlled jet injection using a compound ampoule [J].
McKeage, James W. ;
Ruddy, Bryan P. ;
Nielsen, Poul M. F. ;
Taberner, Andrew J. .
JOURNAL OF CONTROLLED RELEASE, 2018, 291 :127-134
[8]   Analysis of 3-D Effects in Segmented Cylindrical Quasi-Halbach Magnet Arrays [J].
Meessen, K. J. ;
Paulides, J. J. H. ;
Lomonova, E. A. .
IEEE TRANSACTIONS ON MAGNETICS, 2011, 47 (04) :727-733
[9]   Analysis and design of a slotless tubular permanent magnet actuator for high acceleration applications [J].
Meessen, K. J. ;
Paulides, J. J. H. ;
Lomonova, E. A. .
JOURNAL OF APPLIED PHYSICS, 2009, 105 (07)
[10]   Innovation - Current status and future prospects of needle-free liquid jet injectors [J].
Mitragotri, Samir .
NATURE REVIEWS DRUG DISCOVERY, 2006, 5 (07) :543-548