Photonic Carbon Dots as an Emerging Nanoagent for Biomedical and Healthcare Applications

被引：239

作者：

Chung, You Jung ^{[1
]}

Kim, Jinhyun ^{[1
]}

Park, Chan Beum ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol KAIST, Dept Mat Sci & Engn, Daejeon 34141, South Korea

来源：

ACS NANO | 2020年 / 14卷 / 06期

基金：

新加坡国家研究基金会;

关键词：

carbon dots; photonic nanoagents; bioimaging; biosensor; photodynamic therapy; photothermal therapy; photomedicine; nanomedicine; theranostics; healthcare; GRAPHENE QUANTUM DOTS; HIGHLY SENSITIVE DETECTION; BETA-AMYLOID AGGREGATION; GUIDED DRUG-DELIVERY; FULL-COLOR EMISSION; ONE-POT SYNTHESIS; INNER FILTER; FLUORESCENT-PROBES; PHOTOELECTROCHEMICAL SENSORS; POLYETHYLENE-GLYCOL;

D O I：

10.1021/acsnano.0c02114

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

As a class of carbon-based nanomaterials, carbon dots (CDs) have attracted enormous attention because of their tunable optical and physicochemical properties, such as absorptivity and photoluminescence from ultraviolet to near-infrared, high photostability, biocompatibility, and aqueous dispersity. These characteristics make CDs a promising alternative photonic nanoagent to conventional fluorophores in disease diagnosis, treatment, and healthcare managements. This review describes the fundamental photophysical properties of CDs and highlights their recent applications to bioimaging, photomedicine (e.g., photodynamic/photothermal therapies), biosensors, and healthcare devices. We discuss current challenges and future prospects of photonic CDs to give an insight into developing vibrant fields of CD-based biomedicine and healthcare.

引用

页码：6470 / 6497

页数：28

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