ERM proteins: Head-to-tail regulation of actin-plasma membrane interaction

被引：275

作者：

Tsukita, S ^{[1
]}

Yonemura, S ^{[1
]}

Tsukita, S ^{[1
]}

机构：

[1] KYOTO UNIV,FAC MED,DEPT CELL BIOL,KYOTO 606,JAPAN

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1997年 / 22卷 / 02期

关键词：

D O I：

10.1016/S0968-0004(96)10071-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

ERM (ezrin/radixin/moesin) proteins crosslink actin filaments with plasma membranes. The carboxyl termini of these proteins bind actin filaments, while the amino termini bind plasma membranes using a binding partner, such as CD44. Specific signals activate ERM proteins to bind actin filaments and the plasma membrane; these include phosphoinositides and/or phosphorylation mechanisms, which might be located downstream from the Rho-dependent pathway.

引用

页码：53 / 58

页数：6

共 37 条

[1] MEMBRANE-ACTIN MICROFILAMENT CONNECTIONS - AN INCREASING DIVERSITY OF PLAYERS RELATED TO BAND-4.1
ARPIN, M
ALGRAIN, M
LOUVARD, D
[J]. CURRENT OPINION IN CELL BIOLOGY, 1994, 6 (01) : 136 - 141
[2] THE SCHIZOSACCHAROMYCES-POMBE CDC3+ GENE ENCODES A PROFILIN ESSENTIAL FOR CYTOKINESIS
BALASUBRAMANIAN, MK
HIRANI, BR
BURKE, JD
GOULD, KL
[J]. JOURNAL OF CELL BIOLOGY, 1994, 125 (06) : 1289 - 1301
[3] EZRIN OLIGOMERS ARE MAJOR CYTOSKELETAL COMPONENTS OF PLACENTAL MICROVILLI - A PROPOSAL FOR THEIR INVOLVEMENT IN CORTICAL MORPHOGENESIS
BERRYMAN, M
GARY, R
BRETSCHER, A
[J]. JOURNAL OF CELL BIOLOGY, 1995, 131 (05) : 1231 - 1242
[4] BERRYMAN M, 1993, J CELL SCI, V105, P1025
[5] A CD44-LIKE ENDOTHELIAL-CELL TRANSMEMBRANE GLYCOPROTEIN (GP116) INTERACTS WITH EXTRACELLULAR-MATRIX AND ANKYRIN
BOURGUIGNON, LYW
LOKESHWAR, VB
HE, J
CHEN, X
BOURGUIGNON, GJ
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1992, 12 (10) : 4464 - 4471
[6] PURIFICATION OF AN 80,000-DALTON PROTEIN THAT IS A COMPONENT OF THE ISOLATED MICROVILLUS CYTOSKELETON, AND ITS LOCALIZATION IN NON-MUSCLE CELLS
BRETSCHER, A
[J]. JOURNAL OF CELL BIOLOGY, 1983, 97 (02) : 425 - 432
[7] THE SMALL GTP-BINDING PROTEIN-RHO REGULATES A PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE IN MAMMALIAN-CELLS
CHONG, LD
TRAYNORKAPLAN, A
BOKOCH, GM
SCHWARTZ, MA
[J]. CELL, 1994, 79 (03) : 507 - 513
[8] IDENTIFICATION OF DROSOPHILA CYTOSKELETAL PROTEINS BY INDUCTION OF ABNORMAL-CELL SHAPE IN FISSION YEAST
EDWARDS, KA
MONTAGUE, RA
SHEPARD, S
EDGAR, BA
ERIKSON, RL
KIEHART, DP
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (10) : 4589 - 4593
[9] MICROFILAMENT-ORGANIZING CENTERS IN AREAS OF CELL CONTACT - CYTOSKELETAL INTERACTIONS DURING CELL ATTACHMENT AND LOCOMOTION
GEIGER, B
AVNUR, Z
RINNERTHALER, G
HINSSEN, H
SMALL, VJ
[J]. JOURNAL OF CELL BIOLOGY, 1984, 99 (01) : S83 - S91
[10] Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate
Gilmore, AP
Burridge, K
[J]. NATURE, 1996, 381 (6582) : 531 - 535

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