Prospective Non-Randomized Trial Comparing Esophagectomy versus Chemoradiation for Potentially-Resectable Esophageal Cancer: Preliminary Findings

被引：0

作者：

Fujita, H. ^{[1
]}

Tanaka, T. ^{[1
]}

Tanaka, Y. ^{[1
]}

Matono, S. ^{[1
]}

Tsubuku, T. ^{[1
]}

Nishimura, K. ^{[1
]}

Shirouzu, K. ^{[1
]}

机构：

[1] Kurume Univ, Sch Med, Dept Surg, Kurume, Fukuoka 830, Japan

来源：

PROCEEDINGS OF THE 11TH WORLD CONGRESS OF THE INTERNATIONAL SOCIETY FOR DISEASES OF THE ESOPHAGUS | 2008年

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Based on informed consent, patients with it potentially-resectable (T2T3) squamous cell cancer of the esophagus chose either surgery or definitive chemoradiation. The surgical procedure was transthoracic esophagectomy with lymphadenectomy. Definitive chemoradilation was consisted of 60Gy radiation with two cycles of concurrent chemotherapy using CDDP and 5FU. From 2003 to 2007, 1 17 patients prospectively entered this trial in Kurume University Hospital. Ninty-three patients chose surgery, while 24 patients chose chemoradation. The three-year survival rate wits 56% for the surgery group, Mid 39% for the chemoradiation group, with no significant difference. None received salvage esophagectomy. Chemoradiation may be an effective standard treatment for potentially-resectable squamous cell cancer of the esophagus.

引用

页码：131 / 134

页数：4

共 3 条

[1]

Bedenne L, 2007, J CLIN ONCOL, V25, P1160, DOI 10.1200/JCO.2005.04.7118

[2]

MIYAZAKI S, 2004, NIPPON GEKA GAKKAI Z, V105, P484

[3] Chemoradiation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus [J].

Stahl, M ;

Stuschke, M ;

Lehmann, N ;

Meyer, HJ ;

Walz, MK ;

Seeber, S ;

Klump, B ;

Budach, W ;

Teichmann, R ;

Schmitt, M ;

Schmitt, G ;

Franke, C ;

Wilke, H .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (10) :2310-2317

← 1 →